Acoforestinine
Acoforestinine is a natural product from Aconitum handelianum.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Sci Rep.2018, 8(1)
Korean Journal of Pharmacognosy.2019, 50(1):65-71
PLoS One.2017, 12(3):e0173585
J Appl Toxicol.2024, jat.4615.
Plant Biotechnology Reports 2021, 15:117-124.
Neurochem Int.2023, 167:105537.
Mol Med Rep.2015, 12(5):7789-95
Phytochemistry2018, 15:83-92
Nutr Res Pract2019, 13:e45
Eur J Pharmacol.2024, 981:176883.
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Zhongguo Zhong Yao Za Zhi. 2009 Aug;34(15):1927-9.
Diterpenoid alkaloids from Aconitum handelianum.[Pubmed:
19894536]
To investigate the alkaloids from Aconitum handelianum.
METHODS AND RESULTS:
The column chromatographic methods were employed for the isolation and purification of the chemical constituents. The structures were elucidated by spectroscopic methods.
Eight diterpenoid alkaloids were isolated and identified as acoforine (1), Acoforestinine (2), 14-O-acetylsachaconitine (3), vilmorrianine C (4), vilmorrianine D (5), talatizamine (6), chasmanine (7) and yunaconitine (8).
CONCLUSIONS:
All compounds were isolated from this plant for the first time.
