Deacetylasperulosidic acid methyl ester
Ddeacetylasperulosidic acid methyl ester can lower the blood glucose level in normal mice.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Four iridoidal glycosides, deacetylasperulosidic acid methyl ester (DE), scandoside methyl ester (SC), geniposide (GE) and gardenoside (GA) isolated from Gardenia jasminoides Ellis grandiflora Makino leaves, were tested hypoglycemic activity in mice. DE l[Pubmed: 8820933
METHODS AND RESULTS:
Four iridoidal glycosides, Deacetylasperulosidic acid methyl ester (DE), scandoside methyl ester (SC), geniposide (GE) and gardenoside (GA) isolated from Gardenia jasminoides Ellis grandiflora Makino leaves, were tested hypoglycemic activity in mice. DE lowered the blood glucose level in normal mice.
However, SC, GE and GA did not affect the blood glucose level in normal mice, indicating that the absolute configuration of 6 position hydroxy based (OH) should be essential for the biological activity.
A coumarin glucoside from xeromphis obovata.[Reference: WebLink
From root bark of Xeromphis obovata three coumarins have been isolated: scopoletin, its 7-β-d-glucopyranoside (scopolin) and the new β-d-apiosyl-(1” »6′)-β-d-glucopyranoside of scopoletin, named xeroboside. Also two iridoids, Deacetylasperulosidic acid methyl ester and gardenoside, have been isolated and identified as the corresponding acetyl derivatives.