Citrostadienol
Citrostadienol shows cytotoxic activity against B16F10 melanoma cells.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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J Ethnopharmacol.2023, 309:116302.
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Institute of Food Science & Technology2021, 45(9).
Nutrients.2020, 12(12):3638.
Invest New Drugs.2017, 35(2):166-179
Phytother Res.2019, 33(7):1784-1793
Food Chem.2016, 191:81-90
Int J Mol Sci.2018, 19(9):E2601
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J Ethnopharmacol. 2013 Oct 28;150(1):263-9.
Antitumoural effect of Synadenium grantii Hook f. (Euphorbiaceae) latex.[Pubmed:
24008110]
METHODS AND RESULTS:
The Synadenium grantii latex exhibited decreased cell viability of the melanoma line in a concentration and time-dependent manner, and also cell cycle arrest in the S-G2/M phase. The latex caused a 40% reduction in the volume of tumours of the mice with melanomas. Histological examination of the organs of these animals showed no differences between groups. The phytochemical investigation resulted in the isolation and identification of triterpene euphol and the steroid Citrostadienol, which were tested against the strain of melanoma. Euphol showed no antitumoural activity, while the steroid Citrostadienol showed reduced cytotoxic activity.
CONCLUSIONS:
The Synadenium grantii latex presented in vitro and in vivo cytotoxic effects with antitumoural activity against B16F10 melanoma cells.
Nat Prod Res. 2017 Jan;31(1):84-88.
Sterols and squalene in apricot (Prunus armeniaca L.) kernel oils: the variety as a key factor.[Pubmed:
26745662]
METHODS AND RESULTS:
The profile of sterols and squalene content in oils recovered from the kernels of 15 apricot (Prunus armeniaca L.) varieties were investigated. Nine sterols (campesterol, β-sitosterol, Δ5-avenasterol, 24-methylene-cycloartanol, cholesterol, gramisterol, Δ7-stigmasterol, Δ7-avenasterol and Citrostadienol) were identified in apricot kernel oils.
CONCLUSIONS:
The β-sitosterol was the predominant sterol in each cultivar and consisted of 76-86% of the total detected sterols.
The content of total sterols and squalene were significantly affected by the variety and ranged between 215.7-973.6 and 12.6-43.9 mg/100 g of oil, respectively.
