Calycanthoside
Isofraxidin-7-O-glucoside(Calycanthoside ) has the anti-inflammatory effect, it has inhibitory activity on NO production.It also shows antibacterial activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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China Medical Herald, 2016, 13(13):20-3.
Anti-inflammatory constituents of Acanthopanax senticosus[Reference:
WebLink]
To study the anti-inflammatory constituents of Acanthopanax senticosus.
METHODS AND RESULTS:
NO production in the activated RAW 264.7 macrophages induced by LPS and IFN-γ were used to evaluate anti-inflammatory activity. The compounds were isolated by HPD 100 resin, silica gel, ODS and HPLC methods, their structures were identified by Infrared TLC method and spectral imaging spectrum technology. The extraction of A. senticosus. had inhibitory activity on NO production. Seven compounds were isolated and identified as Syringin, Isofraxidin-7-O-glucoside(Calycanthoside),, Syringaresinoldi-O-β-D-glycoside, Sesamin, Daucosterol, β-sitosterol and Vanillic acid respectively.
CONCLUSIONS:
The extraction of A. senticosus. has the anti-inflammatory effect, and phenylpropanoids are the anti-inflammatory constituents.
Zhongguo Zhong Yao Za Zhi,2008,33(15):1843-6.
Studies on chemical constituents and antibacterial activity from n-butanol extract of Sarcandra glabra[Pubmed:
19007012]
To study the chemical constituents and the antibacterial activity from n-butanol extract of Sarcandra glabra.
METHODS AND RESULTS:
The compounds were isolated by Diaion HP-20, Sephadex LH-20, MCI CHP-20 and silica gel column chromatographic methods. Their structures were identified on the basis of physicochemical and spectroscopic analysis. The antibacterial effect of the compounds were measured against Staphylococcus aureus by filterpaper slice method, finally the antibacterial ring in each group was recorded after 24 hours. Seven constituents were isolated and elucidated as 5, 7, 3', 4'-tetrahydroxy-6-C-beta-D-glucopyranosylflavanone(1),kaempferol-3-O-beta-D-glucuronide (2),fraxidin (3),isofraxidin (4),isofraxidin-7-O-beta-D-glucopyranoside(Calycanthoside) (5),kaempferol (6), pinostrobin (7).
CONCLUSIONS:
Diameters (in mm) of antibacterial ring in the compounds 2, 5, 6 were orderly recorded as follows: 14.67 +/- 0.08, 11.14 +/- 1.06, 8.26 +/- 1.26 and the compound 4 is not effective. Compounds 1-3 and 5 were isolated from S. glabra for the first time.
