Barpisoflavone A
Barpisoflavone A possesses moderate estrogen partial agonistic activities and moderate antioxidant activities.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Biosci Biotechnol Biochem. 2016;80(4):774-8.
Biological activities of unique isoflavones prepared from Apios americana Medik.[Pubmed:
26806328]
METHODS AND RESULTS:
Four unique isoflavone aglycones (Barpisoflavone A (1), 2'-hydroxygenistein (2), 5-methylgenistein (3), and gerontoisoflavone A (4)) whose structures were related to genistein were prepared from the tuber of Apios americana Medik. We examined the estrogen receptor and androgen receptor binding activities, estrogen agonistic activities, antioxidant activities, and α-glucosidase inhibitory activities of 1-4.
CONCLUSIONS:
The results obtained showed that 2 possessed potent and 1, 3, and 4 possessed moderate estrogen partial agonistic activities, 1 and 2 possessed moderate antioxidant activities, and 2 and 3 possessed moderate α-glucosidase inhibitory activities.
Agricultural and biological chemistry.1986 July23;50(7):1809-1819.
New 5-O-Methylisoflavones in the Roots of Yellow Lupin : Lupinus luteus L. cv. Barpine(Organic Chemistry).[Reference:
WebLink]
METHODS AND RESULTS:
In addition to 5-O-methylgenistein (1), a further investigation of the isoflavonoid constituents in roots of the yellow lupin (Lupinus luteus L. cv. Barpine) has yielded five new 5-O-methylisoflavones named Barpisoflavone A (2), 5-O-methyl-lupiwighteone (3), barpisoflavone B (4), 5-O-methylderrone (5) and barpisoflavone C (6).
CONCLUSIONS:
These isoflavones were identified by physicochemical methods involving the use of other lupin isoflavones as reference compounds.
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