Anemarsaponin BIII

Anemarsaponin BIII
Product Name Anemarsaponin BIII
CAS No.: 142759-74-8
Catalog No.: CFN90778
Molecular Formula: C45H74O18
Molecular Weight: 903.1 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The rhizomes of Anemarrhena asphodeloides Bunge
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price:
Reference standards.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Baihe Zhimu Tang (BZT) is a famous traditional Chinese medicine recipe to treat dry coughing due to yin deficiency and for moisturizing the lungs. Zhimu is an essential ingredient in BZT used to treat inflammation, fever and diabetes. The most important active components in Zhimu are flavonoids such as neomangiferin, mangiferin, and steroid saponins (e.g., timosaponin BII, Anemarsaponin BIII, timosaponin AIII).
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    The aim of this study was to compare the pharmacokinetics of mangiferin, neomangiferin, timosaponin BII, Anemarsaponin BIII and timosaponin AIII in rat plasma after oral administration of BZT and Zhimu extract (ZME). A sensitive, reliable and robust LC-MS/MS method to simultaneously determine steroid saponins and flavonoids in rat plasma was successfully validated. Significant differences (p < 0.05) were found in the pharmacokinetic parameters of timosaponin BII, Anemarsaponin BIII and timosaponin AIII between BZT and ZME.
    CONCLUSIONS:
    It was surmised that formula compatibility could significantly influence the pharmacokinetics of BZT and our study is the first to study the administration of BZT based on pharmacokinetic studies.
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