8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone
8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone may have antifungal activity against phytopathogenic and human pathogenic fungi.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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An Acad Bras Cienc. 2007 Jun;79(2):215-22.
Complete H-1 and C-13 NMR assignments and antifungal activity of two 8-hydroxy flavonoids in mixture.[Pubmed:
17625676]
METHODS AND RESULTS:
A mixture of the two new flavonols 8-hydroxy-3,4',5,6,7-pentamethoxyflavone (1) and 8-hydroxy-3,3',4' 5,6,7-hexamethoxyflavone (8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone,2) was isolated from a commercial sample of Citrus aurantifolia.
An array of one- ((HNMR)-H-1, {H-1}-C-13 NMR, and APT-C-13 NMR) and two-dimensional NMR techniques (COSY, NOESY, HMQC and HMBC) was used to achieve the structural elucidation and the complete H-1 and C-13 chemical shift assignments of these natural compounds.
CONCLUSIONS:
In addition, the antifungal activity of these compounds against phytopathogenic and human pathogenic fungi was investigated.
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