1-Methyl-2-nonylquinolin-4(1H)-one

1-Methyl-2-nonylquinolin-4(1H)-one
Product Name 1-Methyl-2-nonylquinolin-4(1H)-one
CAS No.: 68353-24-2
Catalog No.: CFN96290
Molecular Formula: C19H27NO
Molecular Weight: 285.4 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The fruits of Evodia rutaecarpa (Juss.) Benth.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
1-Methyl-2-nonylquinolin-4(1H)-one has anti-inflammatory activity, it exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 microM.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • PLoS One.2021, 16(6):e0248479.
  • Sci Rep.2023, 13(1):13610.
  • Reprod Sci.2022,10.1007/s43032-022-01117-4.
  • Anticancer Res.2024, 44(3):1033-1044.
  • Lab Chip.2018, 18(6):971-978
  • Int Immunopharmacol. 2020, 83:106403.
  • Journal of Analytical Chemistry2017, 854-861
  • Evid-Based Compl Alt2020, 7202519:13
  • Horticulturae2022, 8(10), 975.
  • Front Cell Dev Biol.2021, 9:638174.
  • Antidesmone

    Catalog No: CFN98213
    CAS No: 222629-77-8
    Price: Inquiry(manager@chemfaces.com)
    1-Hydroxyacridone

    Catalog No: CFN89240
    CAS No: 65582-54-9
    Price: Inquiry(manager@chemfaces.com)
    1,7-Dihydroxyacridone

    Catalog No: CFN96973
    CAS No: 112649-95-3
    Price: Inquiry(manager@chemfaces.com)
    1-Hydroxy-N-methylacridone

    Catalog No: CFN89268
    CAS No: 16584-54-6
    Price: Inquiry(manager@chemfaces.com)
    1,3-Dihydroxy-4-methoxy-10-methylacridin-9(10H)-one

    Catalog No: CFN99297
    CAS No: 1189362-86-4
    Price: Inquiry(manager@chemfaces.com)
    Arborinine

    Catalog No: CFN89147
    CAS No: 5489-57-6
    Price: Inquiry(manager@chemfaces.com)
    Rutacridone

    Catalog No: CFN89259
    CAS No: 17948-33-3
    Price: Inquiry(manager@chemfaces.com)
    Sambutoxin

    Catalog No: CFN99672
    CAS No: 160047-56-3
    Price: Inquiry(manager@chemfaces.com)
    1-Methyl-2-pentyl-4(1H)-quinolinone

    Catalog No: CFN98094
    CAS No: 22048-98-2
    Price: $218/10mg
    Schinifoline

    Catalog No: CFN97283
    CAS No: 80554-58-1
    Price: $228/10mg
    Planta Med. 2004 Oct;70(10):904-8.
    Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa.[Pubmed: 15490316]

    METHODS AND RESULTS:
    The n-hexane extract of the fruits of Evodia rutaecarpa showed a considerable inhibiting effect on leukotriene biosynthesis in human granulocytes. Bioassay-guided fractionation of the extract led to the isolation of the 5 quinolone alkaloids: 1-methyl-2-nonyl-4(1H)-quinolinone(1-Methyl-2-nonylquinolin-4(1H)-one), 1-methyl-2-(6Z)-6-undecenyl-4(1H)-quinolinone, 1-methyl-2-(4Z,7Z)-4,7-tridecadienyl-4(1H)-quinolinone, evocarpine and 1-methyl-2-(6Z,9Z)-6,9-pentadecadienyl-4(1H)-quinolinone. The compounds exhibited inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1, 10.0, 10.1, 14,6 and 12.3 microM, respectively.
    CONCLUSIONS:
    Structure elucidation of the compounds was achieved by 1D and 2D NMR experiments and comparison of spectral data with literature data.
    Poricoic acid B

    Catalog No: CFN95050
    CAS No: 137551-39-4
    Price: $318/20mg
    2-O-cinnamoyl-beta-D-glucose

    Catalog No: CFN95111
    CAS No: N/A
    Price: $318/20mg
    Dehydrojuncusol

    Catalog No: CFN95143
    CAS No: 117824-04-1
    Price: $318/5mg
    Bruceantinol B

    Catalog No: CFN95216
    CAS No: 1822332-33-1
    Price: $318/5mg
    New compound 7

    Catalog No: CFN95330
    CAS No: N/A
    Price: $368/5mg
    Foliachinenoside C

    Catalog No: CFN95361
    CAS No: 1041180-87-3
    Price: $368/5mg
    2,3-Dehydrosilychristin

    Catalog No: CFN95370
    CAS No: 57499-41-9
    Price: $318/5mg
    10-Hydroxyaloin B

    Catalog No: CFN95454
    CAS No: 134863-92-6
    Price: $318/5mg
    Maingayone

    Catalog No: CFN95479
    CAS No: 271585-66-1
    Price: $318/10mg
    N-Methyltetrahydrocolumbamine

    Catalog No: CFN95590
    CAS No: 92758-34-4
    Price: $318/10mg