1-Cinnamoyl-3-hydroxypyrrolidine
1-Cinnamoyl-3-hydroxypyrrolidine is a natural product from Piper nigrum.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Arch Toxicol.2024, 98(5):1415-1436.
Mol Pharmacol.2021, 99(2):163-174.
Phytochemistry Letters2015, 243-247
LWT2021, 150:112021.
JMSACL2023, 09.002
J Cell Mol Med.2018, 22(9):4236-4242
J Mol Recognit.2020, 33(2):e2819
Korean J of Food Science&Technology 2017, 49(2):146-150
J Chromatogr B Analyt Technol Biomed Life Sci.2020, 1149:122123.
The Korea Society of Pha.2014, 300-314
Related and Featured Products
Planta Med. 2017 Jan;83(1-02):143-50.
Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum.[Pubmed:
27405106]
METHODS AND RESULTS:
Sixty-three amide alkaloids, including three new, piperflaviflorine A (1), piperflaviflorine B (2), and sarmentamide D (4), and two previously synthesized ones, (1E,3S)-1-Cinnamoyl-3-hydroxypyrrolidine (3) and N-[7'-(4'-methoxyphenyl)ethyl]-2-methoxybenzamide (5), were isolated from the aerial parts of Piper flaviflorum and Piper sarmentosum.
Their structures were elucidated by detailed spectroscopic analysis and, in case of 3, by single-crystal X-ray diffraction. Most of the isolates were tested for their antifungal and antibacterial activities.
CONCLUSIONS:
Ten amides (6-15) showed antifungal activity against Cryptococcus neoformans ATCC 90 113 with IC50 values in the range between 4.7 and 20.0 μg/mL.
