Vasorelaxation

Arachidonic acid
Catalog No: CFN90058

Arachidonic acid is 1 of only 2 unsaturated fatty acids retained in the ovaries of crustaceans and an inhibitor of HR97g, a nuclear receptor expressed in adult ovaries. Arachidonic acid induces retinal arteriolar vasodilation by inhibiting subcellular Ca(2+)-signaling activity in retinal arteriolar myocytes, most likely through a mechanism involving the inhibition of L-type Ca(2+)-channel activity. Arachidonic acid causes an increase in free cytoplasmic calcium concentration ([Ca2+]i) in differentiated skeletal multinucleated myotubes C2C12 and does not induce calcium response in C2C12 myoblasts.

3,3'',5-Triiodo-L-thyronine Sodium Salt
Catalog No: CFN90069

The administration of 3,3'',5-Triiodo-L-thyronine Sodium Salt (T3) elicited a vasodilatation in C57BL/6 mice even at the lowest concentration (10(-9)M), a maximal relaxation of more than 50% was observed with the concentrations between 10(-9) and 10(-8)M.

(2-Acetoxyethyl)trimethylammonium
Catalog No: CFN00011

(2-Acetoxyethyl)trimethylammonium is a neurotransmitter, cholinergic and miotic agent.It is also a cardiac depressant, and peripheral vasodilator.

Lochnerine
Catalog No: CFN98852

Lochnerine shows potent vasorelaxant activity, it also shows some antitumor activity, it can bring about complete inhibition of cell growth in P388 leukemia cells in vitro.

Vindorosine
Catalog No: CFN98853

Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular smooth muscles.