Vasorelaxation

Cinnamic aldehyde
Catalog No: CFN90321

Cinnamic aldehyde, a COX-2 inhibitor, exhibits cardioprotective, antidepressant-like, anti-leukemia, anti-oxidative and anti-inflammatory properties. Its supplementation can improve glucose and lipid homeostasis in diabetic animals.

Eburicoic acid
Catalog No: CFN90414

Eburicoic acid and TR2 have anti-inflammatory activity, the mechanism is related to the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, they protect the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms. Eburicoic acid has significant anti-liver cancer effects and more distinctive mechanisms.

Centaureidin
Catalog No: CFN90433

Centaureidin augments IFN-gamma promoter activity by approximately four-fold. Centaureidin shows potential vasorelaxant activity. It inhibits dendrite outgrowth from melanocytes by activating Rho, resulting in the inhibition of melanosome transfer from melanocytes to keratinocytes.

Praeruptorin E
Catalog No: CFN90449

Praeruptorin E is a cardiotonic agent with selective cardiac calcium channel agonistic effect, it can relax swine coronary artery and decrease contractility in guinea-pig left atria. Praeruptorin E may be useful in the therapy of lung injury, it can protect mice from hydrochloric acid (HCl)-induced lung injury by inhibiting polymorphonuclear leukocytes (PMNs) influx, IL-6 release and protein exudation.

Vincamine
Catalog No: CFN90464

Vincamine is a plant alkaloid used clinically as a peripheral vasodilator that increases cerebral blood flow and oxygen and glucose utilization by neural tissue to combat the effect of aging. Vincamine has contractile and relaxant actions on the guinea pig trachealis, may be due to the generation of prostaglandins and to changes in the membrane Ca2+ fluxes and/or the intracellular Ca2+ distribution. Vincamine alleviates Amyloid-β 25-35 peptides-induced cytotoxicity in PC12 cells.