Isocorynoxeine
Catalog No: CFN98155
Isocorynoxeine, an isorhynchophylline-related alkaloid, exhibits a dose-dependent inhibition of 5-HT2A receptor-mediated current response with an IC50 of 72.4 μM.
Isocorynoxeine shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage, it exhibits a significant neuroprotective effect against glutamate-induced HT22 cell death at the maximum concentration.
Cornuside
Catalog No: CFN98159
Cornuside has immunomodulatory, and anti-inflammatory activities, it has protective potential against cerebral ischemic injury, may be due to the suppression of intracellular Ca(2+) elevation and caspase-3 activity, and improvements in mitochondrial energy metabolism and antioxidant properties. Cornuside can treat myocardial I/R and protect the liver from CCl₄-induced acute hepatotoxicity, by reducing oxidative stress and suppressing inflammatory responses.
Methyl cinnamate
Catalog No: CFN98198
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, which has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects. It has a wide spectrum of targets including CaMKK2-AMPK, Ca(2+) channels.