7-Acetyllycopsamine | CAS:73544-48-6 | Manufacturer ChemFaces

7-Acetyllycopsamine exhibits antibacterial effects with a MIC of 1.7 mg/ml in E. coli. 7-Acetyllycopsamine, 7-acetylintermedine, and symlandine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals.

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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

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Metabolism, genotoxicity, and carcinogenicity of comfrey.[Pubmed: 21170807]

METHODS AND RESULTS:
Comfrey contains as many as 14 pyrrolizidine alkaloids (PA), including 7-acetylintermedine, 7-Acetyllycopsamine, echimidine, intermedine, lasiocarpine, lycopsamine, myoscorpine, symlandine, symphytine, and symviridine.

Z Naturforsch C. 1999 May-Jun;54(5-6):295-300.

Pyrrolizidine alkaloids from Echium rauwolfii and Echium horridum (Boraginaceae).[Pubmed: 10431383]

METHODS AND RESULTS:
Structures of 12 minor alkaloids were inferred from GLC and GLC-MS analyses: 7-angeloylretronecine, 7-tigloylretronecine, lycopsamine, 7-Acetyllycopsamine, uplandicine, 7-angeloyllycopsamine, 7-tigloyllycopsamine, tigloyl isomer of echimidine, 7-angeloyl-9-(2-methylbutyryl)retronecine, 7-tigloyl-9-(2-methylbutyryl)retronecine, 7-angeloyl-9-(2,3-dihydroxybutyryl)retronecine, and 7-tigloyl-9-(2,3-dihydroxybutyryl)retronecine.

Product Name	7-Acetyllycopsamine
CAS No.:	73544-48-6
Catalog No.:	CFN00288
Molecular Formula:	C₁₇H₂₇NO₆
Molecular Weight:	341.40 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Targets:	Antifection
Source:	The herbs of Eupatorium maculatum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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