Sophoridine
Catalog No: CFN97172
Sophoridine has anti-inflammatory, anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems. Early and short-time applying sophoridine has neuroprotective effect min permanent middle cerebral artery occlusion (pMCAO) rat brain by down-regulating TRAF6 and up-regulating p-ERK1/2 expression, ameliorating brain infaction and edema. Sophoridine also possesses antiviral activities against Coxsackievirus B3, by regulating cytokine expression, may represent a potential therapeutic agent for viral myocarditis.
Sorafenib
Catalog No: CFN90012
Sorafenib is a potent multikinase inhibitor with IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively.Sorafenib together with inhibitors of the β-catenin pathway might be an effective tool in the treatment of pediatric HCC. The combination of Sorafenib with AMPK activators could have beneficial effects on tumor regression by AMPK pathway activation. The combination of metformin or other AMPK activators and Sorafenib could be tested in prospective clinical trials.
Sorbic acid
Catalog No: CFN90061
Sorbic acid is important food preservatives and powerful fungistatic agents, it inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division). Sorbic acid is a more potent uncoupler of the membrane potential than acetic acid, the effect may also slow the rate of ATP synthesis significantly and may thus (partially) explain Sorbic acid's effectiveness.
