Vincetoxicoside B

Vincetoxicoside B
Product Name Vincetoxicoside B
CAS No.: 22007-72-3
Catalog No.: CFN90737
Molecular Formula: C21H20O11
Molecular Weight: 448.38 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Targets: Antifection
Source: The herbs of Hypericum japonicum Thunb.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $100/20mg
Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Food Chemistry: X2023, 101032.
  • J Korean Med Ophthalmol Otolaryngol Dermatol2023, 36(1):1-20.
  • Molecules.2019, 24(6):E1177
  • Chem Biodivers.2023, 20(10):e202300741.
  • Integr Med Res.2017, 6(4):395-403
  • Acta horticulturae2017, 1158:257-268
  • Biochem Systematics and Ecology2017, 11-18
  • Front Plant Sci.2023, 14:1207940.
  • Academic J of Second Military Medical University2018, 39(11)
  • Molecules.2015, 20(10):19172-88
  • Succinic acid

    Catalog No: CFN99100
    CAS No: 110-15-6
    Price: $30/20mg
    Sodium Danshensu

    Catalog No: CFN99163
    CAS No: 67920-52-9
    Price: $40/20mg
    Isoimperatorin

    Catalog No: CFN99107
    CAS No: 482-45-1
    Price: $40/20mg
    Quercetin 3,5,7,3,4-pentamethyl ether

    Catalog No: CFN70262
    CAS No: 1247-97-8
    Price: Inquiry(manager@chemfaces.com)
    Licochalcone D

    Catalog No: CFN93186
    CAS No: 144506-15-0
    Price: Inquiry(manager@chemfaces.com)
    J Asian Nat Prod Res. 2017 Jan;19(1):47-52.
    Chemical constituents from the rhizome of Polygonum paleaceum and their antifungal activity.[Pubmed: 27309618 ]

    METHODS AND RESULTS:
    A new compounds neopaleaceolactoside (1), along with nine known compounds phyllocoumarin (2), quercetin (3), quercitrin (4), quercetin-3-methyl ether (5), Vincetoxicoside B (6), isoquercitrin (7), kaempferol (8), (-)-epicatechin (9), and chlorogenic acid (10), was isolated from Polygonum paleaceum Wall. Their chemical structures were established based on one-dimensional and two-dimensional nuclear magnetic resonance techniques, mass spectrometry and by comparison with spectroscopic data reported. Some selected compounds were screened for their antifungal activity. Quercetin (3), Vincetoxicoside B (6), kaempferol (8), and (-)-epicatechin (9) showed synergistic antifungal activities with the FICI values <0.5.
    CONCLUSIONS:
    A preliminary structure-activity relationship could be observed that free 3-OH in the structure of flavonoids was important for synergistic antifungal activity.
    J Pharm Biomed Anal. 2016 Jan 25;118:228-34.
    Simultaneous determination and pharmacokinetic study of eight components in rat plasma by UHPLC-MS/MS after oral administration of Hypericum japonicum Thunb extract.[Pubmed: 26580819 ]

    METHODS AND RESULTS:
    A rapid and sensitive assay based on ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) was established and validated for the simultaneous determination of gallic acid, protocatechuic acid, vanillic acid, caffeic acid, epicatechin, isoquercitrin, Vincetoxicoside B and quercetin in rat plasma using catechin and daidzein as the internal standards (IS). Plasma samples added internal standards were acidified with formic acid then pretreated by direct protein precipitation with acetonitrile. The separation of eight constituents was achieved on a C18 column with gradient elution using methanol and 0.2% acetic acid aqueous solution as the mobile phase and detected by multiple reaction monitoring using electrospray ionization source in the positive-negative ionization mode. The method was validated for sufficient specificity, precision, accuracy, and sensitivity over the concentration range of 10-6000 ng mL(-1) for gallic acid, 1.5-3000 ng mL(-1) for protocatechuic acid, 10-15000 ng mL(-1) for vanillic acid, 2-3600 ng mL(-1) for caffeic acid, 1.5-3600 ng mL(-1) for epicatechin, 4-6000 ng mL(-1) for isoquercitrin, 2-9000 ng mL(-1) for Vincetoxicoside B, and 20-18000 ng mL(-1) for quercetin. The overall intra‑run precision and the inter‑run precision were showed in the range of 1.0-14.2% and 2.8-12.9%, respectively, and the accuracy was no more than 12.8%.
    CONCLUSIONS:
    This analytical method was successfully applied to investigate the pharmacokinetics of eight ingredients in rats after oral administration of Hypericum japonicum Thunb extract.
    Oroselol

    Catalog No: CFN95001
    CAS No: 1891-25-4
    Price: $358/5mg
    7-Neohesperidosides

    Catalog No: CFN95018
    CAS No: 28383-41-7
    Price: $288/5mg
    Pterodonoic acid

    Catalog No: CFN95183
    CAS No: 62458-42-8
    Price: $413/5mg
    Methyl neochebulinate

    Catalog No: CFN95201
    CAS No: 1236310-34-1
    Price: $398/5mg
    1-(3',5'-dimethoxy)phenyl-2-[4''-O-beta-D-glucopyranosyl (6->1)-O-alpha-L-rhamnopyranosyl]phenylethane

    Catalog No: CFN95285
    CAS No: 1338076-61-1
    Price: $413/5mg
    Glaucoside C

    Catalog No: CFN95300
    CAS No: 81474-89-7
    Price: $318/5mg
    New compound 8

    Catalog No: CFN95341
    CAS No: N/A
    Price: $318/5mg
    Bergamjuicin

    Catalog No: CFN95422
    CAS No: 2376307-20-7
    Price: $318/5mg
    Isorhamnetin-3-O-rutinoside-7-O-glucoside

    Catalog No: CFN95494
    CAS No: 55481-91-9
    Price: $318/5mg
    5-O-Coumaroylquinic acid

    Catalog No: CFN95507
    CAS No: 32451-86-8
    Price: $318/5mg