Isoelemicin
Reference standards.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
J Pharm Biomed Anal.2024, 247:116257.
TCI CO.2019, US20190151281A1
Exp Ther Med.2019, 18(6):4388-4396
Int J Med Sci.2020, 17(5):626-631
Plant Physiol.2024, 194(4):2580-2599.
Journal of Functional Foods2022, 99: 105331.
Nutrients2022, 14(3),695.
Biol Pharm Bull.2018, 41(11):1645-1651
Revista Brasileira de Farmacognosia2024, 34:1091-1100.
Sci Rep. 2017, 8207(7)
Related and Featured Products
Xenobiotica. 1980 May;10(5):371-80.
Metabolism of alkenebenzene derivatives in the rat. III. Elemicin and isoelemicin.[Pubmed:
7415220]
METHODS AND RESULTS:
1. The metabolites of elemicin (3,4,5-trimethoxyallylbenzene) and Isoelemicin (3,4,5-trimethoxypropenylbenzene) in the rat were identified by g.l.c.-mass spectrometry. 2. The major metabolic reactions of elemicin follow the cinnamoyl pathway or the epoxide-diol pathway. The former route gives 3-(3,4,5-trimethoxyphenyl)propionic acid and its glycine conjugate as major urinary metabolites, whereas 3-(3,4,5-trimethoxyphenyl)propane-1,2-diol is the most prominent metabolite of the latter route. Small amounts of the epoxide of the 3-O-demethylated derivative of elemicin were identified in the urine. 3. Isoelemicin was metabolized by both aforementioned pathways; the cinnamoyl pathway predominated and 3-(3,4,5-trimethoxyphenyl)propionic acid was the major urinary metabolite.
CONCLUSIONS:
4. All of the acidic metabolites detected were C6--C3 derivatives and further oxidation to benzoic acid derivatives did not occur. 5. Most of the urinary metabolites were also found in the bile, but in different relative amounts.
