Hot Products

Isosilybin A
Catalog No: CFN91070

Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50 = 1.7-7.6 µM) and diphenolase (IC50 = 12.1-44.9 µM) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction.

Isosilybin B
Catalog No: CFN91071

Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction. Isosilybin B showed inhibitory effect on CYP2C8 activity. It inhibited both monophenolase (IC50 = 1.7-7.6 μM) and diphenolase (IC50 = 12.1-44.9 μM) of tyrosinase.

Isosilychristin
Catalog No: CFN95369

Isosilychristin is an antioxidant with multidrug resistance modulating activity. Isosilychristin significantly induces ABCA1 protein expression without affecting cell viability.Isosilychristin has anticancer and hepatoprotective activity.

Isosinensetin
Catalog No: CFN90806

Isosinensetin shows antioxidant and HIV-1 protease inhibiting activities.

Isospinosin
Catalog No: CFN95350

Isosteviol
Catalog No: CFN90544

Isosteviol possesses various biological activities including anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, neuroprotective, antibacterial, antifungal,and antioxidant effects.Isosteviol plays a protective role in a variety of stress-induced cardiac diseases, it can prevent the prolongation of action potential in hypertrophied cardiomyoctyes by regulating transient outward potassium and L-type calcium channels.

Isotachioside
Catalog No: CFN98398

Isotachioside has15-lipoxygenase (15-LO) inhibitory activities.

Isotanshinone I
Catalog No: CFN90356

Isotanshinone I ,neotanshinone A and cryptotanshinone have different effects on inhibiting proteic activity of P38 and NF-κB signaling pathway,and this effect may be one of main mechanisms of inhibitive inflammation reaction by salvia miltiorrhiza bunge in liver.

Isotanshinone II
Catalog No: CFN92020

Reference standards.

Isotanshinone IIA
Catalog No: CFN90357

Isotanshinone IIA non-competitively inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 11.4±0.6 μM. PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.