Hot Products

12-O-tetradecanoylphorbol-13-acetate
Catalog No: CFN90367

12-O-tetradecanoylphorbol-13-acetate has skin tumor-promoting potential, it induces endogenous FBXO10 mRNA and FBXO10 protein in Jurkat cells, a human T cell line. It provokes cell motility through regulating the expression and function of S100A14 in a KLF4-dependent manner.
13(18)-Oleanen-3-ol
Catalog No: CFN98801

Standard reference
13(18)-Oleanen-3-one
Catalog No: CFN98023

δ-Amyrone(13(18)-Oleanen-3-one), a specific inhibitor of cyclooxygenase-2, possesses anti-inflammatory effects, which may be relevant to the regulation of COX-2; it exerts its protective effect on experimental gastric ulcer by inhibiting NF-κB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-α, IL-6 and NO. δ-Amyrone has protective activity on LPS-induced endotoxic shock, which is attributed to reducing NO production and mediating the pro-inflammatory cytokines, inhibited NF-κB expression.
13(S)-Hydroxyoctadeca-9(Z),11(E)-dienoic acid (13-HODE)
Catalog No: CFN95307

Anti-inflammatory.
13-HODE down-regulates the thrombogenecity of the injured vessel wall surface.
13-HODE prevents cell adhesion to endothelial cells and can inhibit cancer metastasis.
13-Hydroxygermacrone
Catalog No: CFN92648

13-Hydroxygermacrone inhibits UVB-induced upregulation of the mRNA and protein expression levels of MMP-1, MMP-2, and MMP-3 in human keratinocytes (HaCaT). 13-Hydroxygermacrone shows a protective effect against D-GalN/tumor necrosis factor-alpha-induced liver injury in mice at a dose of 50 mg/kg p.o.
13-Hydroxylupanine
Catalog No: CFN92232

13-Hydroxylupanine is a natural product from Cytisus scoparius.
14-Deoxy-11,12-didehydroandrographolide
Catalog No: CFN98666

14-Deoxy-11,12-didehydroandrographolide has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions, it causes negative chronotropic action and antagonised isoproterenol-induced positive chronotropic actions in a non-competitive and dose-dependent manner. 14-Deoxy-11,12-didehydroandrographolide can effectively ameliorate astrocytic pro-inflammatory reactions and prevent PC12 cell death with different efficacies, it may be candidates for treatment of spinal-cord injury and neurodegeneration.
14-Deoxyandrographolide
Catalog No: CFN92802

14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. It desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A.
14-Deoxycoleon U
Catalog No: CFN97924

14-Deoxycoleon U has anti-termitic activity, it is highly active against both wood-decay fungi. 14-Deoxycoleon U shows antibacterial activity against the Gram-positive bacteria Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, and Micrococcus luteus.
15-Hydroxy-7-oxodehydroabietic acid
Catalog No: CFN97533

Standard reference