Yadanziolide A

Yadanziolide A
Product Name Yadanziolide A
CAS No.: 95258-14-3
Catalog No.: CFN96428
Molecular Formula: C20H26O10
Molecular Weight: 426.41 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Targets: Antifection
Source: The seeds of Brucea javanica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $338/10mg
Yadanziolide A shows strong antiviral activity.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Molecules.2017, 22(2)
  • Processes 2021, 9(5),894.
  • Aging (Albany NY).2023, 15(24):15557-15577.
  • Oxid Med Cell Longev.2021, 2021:6647107.
  • Food Addit Contam Part A Chem Anal Control Expo Risk Assess.2020, 37(9):1437-1448.
  • J.Food Processing & Preservation2022, jfpp.16666
  • Cell Signal.2022, 99:110433.
  • OENO One2023, 57:3.
  • Metabolites2023, 13(1), 3.
  • Life (Basel).2021, 11(7):616.
  • Bruceanic acid C

    Catalog No: CFN91975
    CAS No: 132587-60-1
    Price: Inquiry(manager@chemfaces.com)
    Ailanthone

    Catalog No: CFN97561
    CAS No: 981-15-7
    Price: $318/20mg
    Etuycomanol

    Catalog No: CFN95771
    CAS No: 84633-28-3
    Price: $318/10mg
    Eurycomanone

    Catalog No: CFN92008
    CAS No: 84633-29-4
    Price: $268/20mg
    13beta,21-dihydroxyeurycomanone (Pasakbumin C)

    Catalog No: CFN95770
    CAS No: 129587-06-0
    Price: $318/10mg
    Pasakbumin B

    Catalog No: CFN92009
    CAS No: 138809-10-6
    Price: Inquiry(manager@chemfaces.com)
    Bruceine D

    Catalog No: CFN90771
    CAS No: 21499-66-1
    Price: $138/20mg
    Yadanziolide C

    Catalog No: CFN96426
    CAS No: 95258-12-1
    Price: Inquiry(manager@chemfaces.com)
    Yadanziolide B

    Catalog No: CFN96427
    CAS No: 95258-13-2
    Price: Inquiry(manager@chemfaces.com)
    Yadanziolide A

    Catalog No: CFN96428
    CAS No: 95258-14-3
    Price: $338/10mg
    J Agric Food Chem. 2010 Feb 10;58(3):1572-7.
    Anti-tobacco mosaic virus (TMV) Quassinoids from Brucea javanica (L.) Merr.[Pubmed: 20050684 ]
    Two new quassinoids, javanicolide E (1) and javanicolide F (2), along with fifteen known C-20 quassinoids were isolated from the seeds of Brucea javanica (L.) Merr.
    METHODS AND RESULTS:
    The antitobacco mosaic virus (TMV) activity of these quassinoids was screened by the conventional half-leaf and leaf-disk method along with Western blot analysis.
    CONCLUSIONS:
    All of the seventeen quassinoids showed potent anti-TMV activity. Among them, eight compounds, brusatol (3), bruceine B (4), bruceoside B (5), yadanzioside I (6), yadanzioside L (7), bruceine D (8), Yadanziolide A (9), and aglycone of yadanziolide D (17), showed strong antiviral activities, with IC(50) values in the range of 3.42-5.66 microM, and were much more effective than the positive control, ningnanmycin (IC(50) = 117.3 microM). The antiviral structure-activity relationships of quassinoids against TMV were also discussed.
    J Nat Prod. 2007 Oct;70(10):1654-7.
    Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica.[Pubmed: 17896817 ]
    Boiled extracts derived from 28 Indonesian medicinal plants were screened for their antibabesial activity against Babesia gibsoni in vitro.
    METHODS AND RESULTS:
    Of these extracts, the fruit of Brucea javanica was the most active in inhibiting parasite growth at a concentration of 10 microg/mL. Bioassay-guided fractionation of the fruit extract of Br. javanica led to the isolation of two new quassinoids, bruceantinol B and bruceine J, and the structures of these compounds were elucidated on the basis of their spectroscopic data and by chemical transformation to known compounds. In addition, the known quassinoids bruceines A-D, bruceantinol, and Yadanziolide A were isolated.
    CONCLUSIONS:
    Antibabesial activities were also examined in vitro, and bruceine A and bruceantinol were shown to be more potent than diminazene aceturate, a drug (IC50 = 103 ng/mL) used clinically against B. gibsoni, with IC50 values of 4 and 12 ng/mL, respectively.
    Chemical & Pharmaceutical Bulletin, 1984 , 32 (11) :4698-701.
    Structures of yadanziolides A, B, and C, new bitter principles from Brucea javanica.[Reference: WebLink]
    Three bitter quassinoids, Yadanziolide A, yadanziolide B, and yadanziolide C (1, 2 and 3), were isolated from seeds of Brucea javanica, known as"Ya-dan-zi" in Chinese folklore and their structures have been established from chemical transformation and spectral analysis.
    Parvisoflavanone

    Catalog No: CFN95077
    CAS No: 49776-79-6
    Price: $413/5mg
    Stevioside D

    Catalog No: CFN95230
    CAS No: 1310055-59-4
    Price: $463/5mg
    New compound 5

    Catalog No: CFN95258
    CAS No: N/A
    Price: $413/5mg
    Methyl 2-hydroxy-3,4-dimethoxybenzoate

    Catalog No: CFN95383
    CAS No: 6395-23-9
    Price: $268/5mg
    Sativanone

    Catalog No: CFN95388
    CAS No: 70561-31-8
    Price: $318/10mg
    Tortoside B (Manglieside E)

    Catalog No: CFN95390
    CAS No: 190655-17-5
    Price: $413/5mg
    3-Hydroxymollugin

    Catalog No: CFN95424
    CAS No: 154706-45-3
    Price: $368/5mg
    New compound 17

    Catalog No: CFN95466
    CAS No: N/A
    Price: $318/5mg
    8-epi-Confertin

    Catalog No: CFN95509
    CAS No: 110115-60-1
    Price: $318/5mg
    New compound 22

    Catalog No: CFN95570
    CAS No: N/A
    Price: $413/5mg