Vicenin -1

Vicenin -1
Product Name Vicenin -1
CAS No.: 35927-38-9
Catalog No.: CFN92030
Molecular Formula: C26H28O14
Molecular Weight: 564.5 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Targets: Aldose reductase
Source: The herbs of Vitex negundo L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $288/5mg
Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity.
Inquire / Order:
Technical Inquiries:
Tel: +86-27-84237783
Fax: +86-27-84254680

1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to:

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Biochem Biophys Res Commun.2017, 494(3-4):587-593
  • Food Funct.2020, 10.1039
  • J Sep Sci.2018, 41(7):1682-1690
  • Nutrients.2019, 12(1)
  • Int J Food Sci Nutr.2019, 70(7):825-833
  • Toxicol Res.2019, 35(4):371-387
  • LWT-Food Science and Technology2017, 75:488-496
  • Chem Biol Interact.2018, 290:44-51
  • Biochemistry.2018, 57(40):5886-5896
  • Front Neurosci.2019, 13:1091
  • Schaftoside

    Catalog No: CFN90197
    CAS No: 51938-32-0
    Price: $100/20mg

    Catalog No: CFN92071
    CAS No: 61328-41-4
    Price: $368/5mg
    Vicenin -1

    Catalog No: CFN92030
    CAS No: 35927-38-9
    Price: $288/5mg

    Catalog No: CFN92029
    CAS No: 52012-29-0
    Price: $288/20mg
    Vicenin -2

    Catalog No: CFN92031
    CAS No: 23666-13-9
    Price: $188/10mg
    Isovitexin 2''-O-arabinoside

    Catalog No: CFN90943
    CAS No: 53382-71-1
    Price: $318/10mg

    Catalog No: CFN99341
    CAS No: 1223097-20-8
    Price: Inquiry(
    Meloside A

    Catalog No: CFN90132
    CAS No: 60767-80-8
    Price: Inquiry(

    Catalog No: CFN90133
    CAS No: 19416-87-6
    Price: $368/5mg

    Catalog No: CFN90131
    CAS No: 53452-16-7
    Price: $118/20mg
    Journal of the Korean Society for Applied Biological Chemistry, 2015, 58(3):365-371.
    Plant-derived molecules from Saussurea grandifolia as inhibitors of aldose reductase.[Reference: WebLink]
    Saussurea grandifolia was tested for aldose reductase (AR) inhibition as part of a search for potentially therapeutic natural compounds.
    Stepwise polarity fractions were tested for in vitro inhibition of rat lens AR. Of these, the ethyl acetate (EtOAc) and n-butanol (n-BuOH) fractions exhibited AR inhibitory activities. A chromatographic separation of the active EtOAc and n-BuOH fractions led to the isolation of nine compounds, which were known and identified as vitexin (1), genkwanin-5-O-glucoside (2), vitexin 2″-p-hydroxybenzoate (3), kaempferol-3-O-rutinoside (4), isovitexin (5), quercitrin (6), isoquercitrin (7), 1,5-di-O-caffeoylquinic acid (8), and Vicenin -1 (9). Among these compounds, compounds 6, 7, and 8 showed very strong inhibitory activities against AR (IC50’s = 0.34, 0.32, and 0.08 μM, respectively).
    The results suggest that S. grandifolia is clearly a potential source for therapeutic agent that might be useful for the treatment of diabetic complications.
    Regulatory Toxicology and Pharmacology, 2016:S0273230016303026.
    Acute and repeated doses (28 days) oral toxicity study of Vicenin-1, a flavonoid glycoside isolated from fenugreek seeds in laboratory mice.[Reference: WebLink]
    Vicenin -1 (fenugreek glycoside) has been proven to possess potent anti-inflammatory and anti-oxidant activity. The objective of the present investigation was to determine in-vivo acute and subacute (28-days repeated dose) oral toxicity of Vicenin -1 isolated from fenugreek seed.
    Vicenin-1 (93%) was isolated from a hydroalcoholic extract of fenugreek seed and characterized using HPLC, TLC, 1H NMR and 13C NMR. Acute oral toxicity (AOT) and subacute toxicity studies of Vicenin -1 were carried out according to OECD 425 (up-and-down procedure) and OCED 407 guidelines in Swiss albino mice. In AOT, Vicenin -1showed 10% mortality when administered at a dose of 5000 mg/kg. However, when vicenin-1 was administered for at doses of 37.5, 75, or 150 mg/kg 28-days it did not show any mortality at the administered doses. Vicenin -1 (75 mg/kg) did not show observational, behavioral, biochemical or histopathological toxic effects. There were minor alterations in body weight, hematology, and histopathology of mice administered with Vicenin -1 (150 mg/kg), but these changes were within normal laboratory ranges. The highest concentration of Venicin-1 was found in liver (3.46%) followed by lung (0.65%).
    In conclusion, Vicenin -1 showed median lethal dose (LD50) of 4837.5 mg/kg with no-observed-adverse-effect levels (NOAEL) at 75 mg/kg and lowest adverse effect levels (LOAEL) at 150 mg/kg for both sexes of mice during AOT and sub-acute toxicity study, respectively.

    Catalog No: CFN99025
    CAS No: 101140-06-1
    Price: $418/5mg

    Catalog No: CFN90386
    CAS No: 18085-97-7
    Price: $198/20mg
    2''-O-Rhamnosylicariside II

    Catalog No: CFN92551
    CAS No: 135293-13-9
    Price: $388/10mg

    Catalog No: CFN95011
    CAS No: 93446-18-5
    Price: $318/10mg

    Catalog No: CFN89280
    CAS No: 36150-23-9
    Price: $318/10mg

    Catalog No: CFN91062
    CAS No: 1425501-89-8
    Price: $332/10mg

    Catalog No: CFN95186
    CAS No: 131623-13-7
    Price: $318/10mg
    Dichotomine B

    Catalog No: CFN95193
    CAS No: 755036-41-0
    Price: $463/5mg
    Schisphenin E

    Catalog No: CFN95223
    CAS No: 1311376-52-9
    Price: $388/5mg
    Ginsenoside Rd2 (Quinquenoside L10)

    Catalog No: CFN95231
    CAS No: 83480-64-2
    Price: $318/10mg