Sylvestroside I
Sylvestroside I may have analgesic effect.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Food Chem.2021, 377:131976.
Biochem Biophys Res Commun.2018, 505(1):261-266
J Med Food.2019, 22(10):1067-1077
Molecules.2023, 28(8):3503.
Front Microbiol.2019, 10:2806
Korean Herb. Med. Inf.2020, 8(2):233-242.
Evid Based Complement Alternat Med.2018, 2018:3610494
Processes2021, 9(5),831.
Metabolites.2020, 10(12):497.
J Food Biochem.2021, 45(7):e13774.
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nternational Journal of Pharmacognosy,1996,34(4):255-61.
Phytochemical and pharmacological studies on medicinal herb Acicarpha tribuloides.[Reference:
WebLink]
METHODS AND RESULTS:
In the present study we report the isolation of five iridoids and bis-iridoids identified as secologanin (I), swerosidic acid (II), secoxyloganin (III), Sylvestroside I (IV) and Sylvestroside III (V) from Acicarpha tribuloides Juss. (Calyceraceae). Also, the pharmacological profile of the extracts (Petroleum ether, CHCl 3, CHCl 3 /MeOH (9:1), MeOH and n-BuOH) from A. tribuloides was studied both in vivo and in vitro experiments. The in vivo experiments indicate that CHCl 3 /MeOH, MeOH and n-BuOH (100, 50 and 10 mg/kg/po) induce a significative analgesic effect in mice whereas CHCl 3 and petroleum ether extracts were inactive. In the in vitro experiments the extracts showed a similar activity because CHCl 3 /MeOH, MeOH and n-BuOH (500,250 and 125 μg/ml) were able to reduce the electrically induced contractions of guinea-pig ileum whereas CHCl 3 and petroleum ether extracts did not.
CONCLUSIONS:
As the active extracts contain iridoids, the pharmacological effects observed appear to depend on these structures.
