Sorokinianin

Sorokinianin
Product Name Sorokinianin
CAS No.: 162616-73-1
Catalog No.: CFN96670
Molecular Formula: C18H28O4
Molecular Weight: 308.42 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Oil
Targets: Antifection
Source: The culture filtrates of the fungus Drechslera cynodontis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Sorokinianin is a phytotoxin, it has antifungal activity, it is highly effective in suppressing spore germination of F. solani (75%) at 100 ug/ml concentration.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Int J Biol Macromol.2021, 199:189-200.
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  • J Nat Prod.2019, 82(4):1002-1008
  • Appl. Sci.2020, 10(16),5482.
  • Arch Biochem Biophys.2018, 644:93-99
  • Ajou University2024, 4688116
  • Phytomedicine.2022, 102:154183.
  • J Microbiol Biotechnol.2024, 35:e2408022.
  • Front Chem.2023, 11:1245071.
  • Int J Med Sci.2024, 21(15):2883-2896
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    Mansoura University Journal of Agricultural Sciences, 2009.
    Fungitoxic activity of two sequiterpene compounds from drechslera cynodontis against plant pathogen fungi.[Reference: WebLink]

    METHODS AND RESULTS:
    Two, sesquiterpenes; Dihydrobipolaroxin (1) and Sorokinianin (2). have been isolated from the culture filtrates of the fungus Drechslera cynodontis.Compound 2 (Sorokinianin) decreased the fungal growth at concentration of 100 μg/ml in all tested fungi which ranged from 22.2% growth inhibition in R. solani to 61.1% in F. solani. Compound 2 was highly effective in suppressing spore germination of F. solani (75%) at 100μg/ml concentration. Data of experiments done to determine the minimum inhibitory concentrations (MIC) for fungal growth indicated that maximum concentration (100 μg/ml) of both compounds was not sufficient for inhibiting completely the growth of all tested fungi.
    CONCLUSIONS:
    All tested compounds recorded higher MIC values (100 μg/ml). The MIC for spore germination Compounds 1 and compounds 2 had less inhibitory effect on spore germination of all tested fungi, they recorded- higher MIC values (100 μg/ml).
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    Sorokinianin: A novel phytotoxin produced by the phytopathogenic fungus Bipolaris sorokiniana[Reference: WebLink]

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    Structure of Sorokinianin, a novel phytotoxin from an isolate of Bipolaris sorokiniana was determined to be 3-hydroxy-5-(8′-hydroxymethyl-4′-isopropyl-1′-methyl-7′-methylenebicyclo[3.2.1]oct-6′-yl)tetrahydro-2-furanone predominantly on the basis of 2D NMR.
    CONCLUSIONS:
    The preliminary incorporation study suggested that this phytotoxin is derived biogenetically not from a geranylgeranylpyrophosphate through removal of two carbons but from a farnesylpyrophosphate and an additional C3 unit.
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