Sibiricin
Standard reference
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Korean Journal of Pharmacognosy2017, 48(4):320-328
Separations2023, 10(2), 131.
Ulm University Medical Center2020, doi: 10.18725.
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Front Cell Infect Microbiol.2018, 8:292
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Plos One.2019, 15(2):e0220084
PLoS One.2018, 13(4):e0195642
Chin. Med.J.Res. Prac.2017, 31(4)
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Tetrahedron.1968;24(8):3247–3253.
Components of seseli sibiricum: Constitution and synthesis of sibiricin, a new coumarin.[Reference:
WebLink]
METHODS AND RESULTS:
From the pet. ether extract of S. sibiricum osthol, imperatorin, bergapten and a new coumarin named Sibiricin have been isolated. It has been assigned 5,7-dimethoxy-coumarin-8-γ,γ-dimethylallyl epoxide structure on the basis of degradative and spectral studies.
CONCLUSIONS:
Final confirmation of the structure has been provided by a synthesis following an unambigous route using 3-dimethylallyl-2-hydroxy-4,6-dimethoxybenzaldehyde as the important intermediate.
Chemical & Pharmaceutical Bulletin, 1996 , 44 (6) :1208-1211.
Prenylcoumarins from Murraya paniculata var. omphalocarpa(Rutaceae): The Absolute Configuration of Sibiricin, Mexoticin and Omphamurin.[Reference:
WebLink]
METHODS AND RESULTS:
Three new prenylcoumarins, murpaniculol senecioate, 5-methoxymurrayatin and omphamurin isovalerate were isolated from the leaves of Murraya paniculata var. omphalocarpa (Rutaceae), together with six known coumarins, paniculatin, (-)-Sibiricin, 5, 7-dimethyoxy-8-(3'-methyl-2'-oxobutyl)coumarin, (-)-mexoticin, omphamurin and omphalocarpin. Their structures were characterizied on the basis of spectroscopic evidence.
CONCLUSIONS:
The absolute configulation of omphamurin at the C-2' position has been determined to be S by Horeau's method. THe absolute stereochemistry of (-)-mexoticin and (-)-Sibiricin has also been established by their chemical correlation with omphamurin.
