Seneganolide
Seneganolide has insect antifeeding activity. Seneganolide A has antifungal activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Nutr Res Pract2019, 13:e45
J Nat Med.2022, 76(1):59-67.
NanoBioScience2024, v13:3:115.
Food Chem.2019, 278:683-691
Int Immunopharmacol.2020, 90:107268.
Plants (Basel).2024, 13(23):3314.
Chemistry of Plant Raw Materials2019, 4:135-147
Rec. Nat. Prod.2024, 18:4,405-418.
Biochem Biophys Res Commun.2020, 522(4):1052-1058
Metabolites2023, 13(1), 3.
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Fitoterapia. 2004 Sep;75(6):566-72.
Antifungal limonoids from the fruits of Khaya senegalensis.[Pubmed:
15351110]
METHODS AND RESULTS:
Investigation of the fruits of Khaya senegalensis resulted in the isolation of three new mexicanolide limonoids containing a rare conjugated diene lactone system named Seneganolide A (1), 2-hydroxySeneganolide A (2) and 2-acetoxySeneganolide A (3). Two known limonoids, 3-deacetyl-7-deacetoxy-7-oxokhivorin (4) and methyl 6-hydroxyangolensate (5), were also found. The structures of the new compounds were elucidated on the basis of spectral methods.
CONCLUSIONS:
The antifungal activity of compounds Seneganolide A, 3 and 5 was tested against the fungus Botrytis cinerea.
Chemistry letters, 2000(8):876-877.
Seneganolide, a Novel Antifeeding Mexicanolide from Khaya senegalensis[Reference:
WebLink]
METHODS AND RESULTS:
Seneganolide, a Novel Antifeeding Mexicanolide from Khaya senegalensis.
Molecules. 2014 Mar 7;19(3):3004-11.
Limonoids from the fruits of Khaya ivorensis.[Pubmed:
24609020]
METHODS AND RESULTS:
Two new limonoids, namely 14,15-didehydroruageanin A (1) and 3-O-methyl- butyrylSeneganolide A (2), were isolated from the fruits of Khaya ivorensis along with six known limonoids: Seneganolide A (3), 1,3-dideacetylkhivorin (4), 7-deacetylkhivorin (5), 3-deacetylkhivorin (6), 1-deacetylkhivorin (7), and 3-deacetyl-7-oxokhivorin (8). All the compounds were evaluated for their cytotoxicity against five tumor cell lines.
