Quercetin 3-O-glucoside-7-O-rhamnoside

Quercetin 3-O-glucoside-7-O-rhamnoside
Product Name Quercetin 3-O-glucoside-7-O-rhamnoside
CAS No.: 18016-58-5
Catalog No.: CFN90738
Molecular Formula: C27H30O16
Molecular Weight: 610.52 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Yellow powder
Source: The herbs of Hippophae rhamnoides Linn.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price: $388/10mg
Quercetin 3-O-glucoside-7-O-rhamnoside at 30 mg/kg i.p. can decrease the ambulatory locomotor activity and increase the sodium thiopental-induced time of loss of the righting reflex suggesting a clear depressant action.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Nanotechnology.2024, ad470d.
  • JMSACL2023, 09.002
  • RSC Adv.2018, 32621-32636
  • Vojnosanit Pregl2016, 75(00):391-391
  • Am J Chin Med.2023, 51(4):1019-1039.
  • Hortic Res.2023, 10(9):uhad154.
  • Evid Based Complement Alternat Med.2017, 2017:7383104
  • Molecules.2022, 27(21):7514.
  • ACS Synth Biol.2020, 9(9):2282-2290.
  • Journal of Third Military Medical University2019, 41(2):110-115
  • 3-Butylidenephthalide

    Catalog No: CFN99588
    CAS No: 551-08-6
    Price: $40/20mg
    Laricitrin

    Catalog No: CFN70400
    CAS No: 53472-37-0
    Price: Inquiry(manager@chemfaces.com)
    Tormentic acid

    Catalog No: CFN99434
    CAS No: 13850-16-3
    Price: $238/10mg
    Pueroside A

    Catalog No: CFN95177
    CAS No: 100692-52-2
    Price: $318/5mg
    (-)-Epigallocatechin gallate

    Catalog No: CFN99569
    CAS No: 989-51-5
    Price: $40/20mg
    Phytother Res. 2009 Oct;23(10):1453-7.
    Neuroactive flavonoid glycosides from Tilia petiolaris DC. extracts.[Pubmed: 19288528]
    Pharmacological assay guided purification of an ethanol extract of Tilia petiolaris DC. inflorescences resulted in the isolation and identification of isoquercitrin (ISO), Quercetin 3-O-glucoside-7-O-rhamnoside (QUE) and kaempferol 3-O-glucoside-7-O-rhamnoside (KAE).
    METHODS AND RESULTS:
    The behavioral actions of these glycosylated flavonoids were examined in the hole board, locomotor activity and thiopental-induced loss of righting reflex tests in mice. Quercetin 3-O-glucoside-7-O-rhamnoside (10 and 30 mg/kg) and KAE (30 mg/kg), intraperitoneally (i.p.) administered to mice, reduced all the parameters measured in the hole board test, but ISO (30 mg/kg) only reduced the number of rearings. Meanwhile Quercetin 3-O-glucoside-7-O-rhamnoside at 30 mg/kg i.p. also decreased the ambulatory locomotor activity and increased the sodium thiopental-induced time of loss of the righting reflex suggesting a clear depressant action.
    CONCLUSIONS:
    The above results demonstrate the occurrence of neuroactive flavonoid glycosides in Tilia.
    Appl Microbiol Biotechnol. 2013 Jun;97(12):5275-82.
    Regioselective synthesis of flavonoid bisglycosides using Escherichia coli harboring two glycosyltransferases.[Pubmed: 23549747 ]
    Regioselective glycosylation of flavonoids cannot be easily achieved due to the presence of several hydroxyl groups in flavonoids.
    METHODS AND RESULTS:
    This hurdle could be overcome by employing uridine diphosphate-dependent glycosyltransferases (UGTs), which use nucleotide sugars as sugar donors and diverse compounds including flavonoids as sugar acceptors. Quercetin rhamnosides contain antiviral activity. Two quercetin diglycosides, Quercetin 3-O-glucoside-7-O-rhamnoside and quercetin 3,7-O-bisrhamnoside, were synthesized using Escherichia coli expressing two UGTs. For the synthesis of Quercetin 3-O-glucoside-7-O-rhamnoside, AtUGT78D2, which transfers glucose from UDP-glucose to the 3-hydroxyl group of quercetin, and AtUGT89C1, which transfers rhamnose from UDP-rhamnose to the 7-hydroxyl group of quercetin 3-O-glucoside, were transformed into E. coli. Using this approach, 67 mg/L of Quercetin 3-O-glucoside-7-O-rhamnoside was synthesized. For the synthesis of quercetin 3,7-O-bisrhamnoside, AtUGT78D1, which transfers rhamnose to the 3-hydroxy group of quercetin, and AtUGT89C1 were used.
    CONCLUSIONS:
    The RHM2 gene from Arabidopsis thaliana was coexpressed to supply the sugar donor, UDP-rhamnose. E. coli expressing AtUGT78D1, AtUGT89C1, and RHM2 was used to obtain 67.4 mg/L of quercetin 3,7-O-bisrhamnoside.
    Glucoliquiritin

    Catalog No: CFN95011
    CAS No: 93446-18-5
    Price: $318/10mg
    Selaginellin F

    Catalog No: CFN95029
    CAS No: 1340493-24-4
    Price: $413/5mg
    20-O-Glucoginsenoside Rf

    Catalog No: CFN95036
    CAS No: 68406-27-9
    Price: $318/5mg
    7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin

    Catalog No: CFN95070
    CAS No: 1092952-62-9
    Price: Inquiry(manager@chemfaces.com)
    Daucoidin A

    Catalog No: CFN95275
    CAS No: 103629-87-4
    Price: $318/5mg
    13(S)-Hydroxyoctadeca-9(Z),11(E)-dienoic acid (13-HODE)

    Catalog No: CFN95307
    CAS No: 18104-45-5
    Price: $318/10mg
    Crepidiaside B

    Catalog No: CFN95432
    CAS No: 101921-35-1
    Price: $318/10mg
    Giganteone C

    Catalog No: CFN95484
    CAS No: 1071223-56-7
    Price: $318/10mg
    Octyl 3-(4-hydroxyphenyl)prop-2-enoate

    Catalog No: CFN95563
    CAS No: N/A
    Price: $318/5mg
    Methyl ganoderate F

    Catalog No: CFN95584
    CAS No: 98665-08-8
    Price: $368/5mg