Polypodine B

Polypodine B
Product Name Polypodine B
CAS No.: 18069-14-2
Catalog No.: CFN89545
Molecular Formula: C27H44O8
Molecular Weight: 496.63 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Achyranthes bidentata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Polypodine B shows growth-promoting effects on in vitro development of the larval endoparasitoid, Venturia canescens (Hymenoptera: Ichneumonidae).
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • JOTCSA.2023, 10(4); 893-902.
  • Neuropharmacology.2018, 131:68-82
  • Nutrients.2019, 11(4):E936
  • Molecules.2017, 22(12)
  • Enzyme and Microbial Technology2022, 110002.
  • Phytother Res.2015, 29(7):1088-96
  • Phytomedicine.2019, 67:153159
  • Int J Oncol.2016, 49(4):1497-504
  • J Med Food.2021, 24(3):209-217.
  • Molecules.2021, 26(4):817.
  • Dihydrocholesterol

    Catalog No: CFN90608
    CAS No: 80-97-7
    Price: $70/20mg
    Cholesterol

    Catalog No: CFN90040
    CAS No: 57-88-5
    Price: $30/20mg
    4-Beta-Hydroxycholesterol

    Catalog No: CFN90611
    CAS No: 17320-10-4
    Price: Inquiry(manager@chemfaces.com)
    7Beta-Hydroxycholesterol

    Catalog No: CFN90610
    CAS No: 566-27-8
    Price: Inquiry(manager@chemfaces.com)
    7-Ketocholesterol

    Catalog No: CFN91812
    CAS No: 566-28-9
    Price: Inquiry(manager@chemfaces.com)
    7-Oxocholesteryl acetate

    Catalog No: CFN91647
    CAS No: 809-51-8
    Price: Inquiry(manager@chemfaces.com)
    27-Hydroxycholesterol

    Catalog No: CFN90609
    CAS No: 20380-11-4
    Price: $218/10mg
    Cholest-4,6-diene-3-ol

    Catalog No: CFN91582
    CAS No: 14214-69-8
    Price: Inquiry(manager@chemfaces.com)
    Ponasterone A

    Catalog No: CFN99419
    CAS No: 13408-56-5
    Price: Inquiry(manager@chemfaces.com)
    Ajugasterone C

    Catalog No: CFN90616
    CAS No: 23044-80-6
    Price: $268/5mg
    J Insect Physiol. 2000 Apr;46(4):467-476.
    Growth-promoting effects of ecdysteroids and juvenile hormone on in vitro development of the larval endoparasitoid, Venturia canescens (Hymenoptera: Ichneumonidae).[Pubmed: 12770211]
    We previously reported that lipophorin, fetal bovine serum (FBS), and 20-hydroxyecdysone (20-HE) are essential for the development of the larval endoparasitoid Venturia canescens larvae in vitro. The present study was undertaken to determine the optimal concentrations of those three substances in the MGM-450 medium, and to examine the hormonal effects of ecdysteroids and juvenile hormone (JH) on the development of the parasitoid larvae in vitro.
    METHODS AND RESULTS:
    When the culture was started with embryos at the post-germband stage, concentrations of 3 mg/ml of lipophorin and 20% of FBS were most suitable for the development of the parasitoid. The growth-promoting effect of 20-HE increased in a concentration-dependent manner and peaked at a concentration of 1 &mgr;g/ml. Excess concentration led to malformations of the larvae. Three other ecdysteroids, ecdysone, 2-deoxy-20-hydroxyecdysone, and Polypodine B had the same effect, although their activity was lower than that of 20-HE. Cholesterol had no effect; most larvae failed to develop. When the medium was supplemented with JH, the duration of the developmental period was significantly shortened, but this hormone was not found to be essential.
    J Insect Sci. 2010;10:13. doi: 10.1673/031.010.1301.
    Dietary effects of four phytoecdysteroids on growth and development of the Indian meal moth, Plodia interpunctella.[Pubmed: 20575744 ]

    METHODS AND RESULTS:
    Using pure phytoecdysteroids isolated from Ajuga iva (L.) Schreber (Lamiales: Lamiaceae) and Silene nutans L. (Caryophyllales: Caryophyllaceae), plants known for their high ecdysteroid content, a study was carried out on the effects of ingestion of four different phytoecdysteroids (20-hydroxyecdysone, Polypodine B, ponasterone A and makisterone A) on the growth and development of the Indian meal moth, Plodia interpunctella Hübner (Lepidoptera: Pyralidae) larvae when added at a concentration of 200 ppm in their diet. The experiments clearly showed the susceptibility of P. interpunctella to phytoecdysteroid ingestion. The toxicity of phytoecdysteroids manifested itself by a decrease in larval weight, induction of cannibalism and an increase of mortality, together with disruption of development. The severity of the phytoecdysteroid effect on P. interpunctella depended on the structure of the molecule. The results demonstrate that the minimal structural differences existing between these four phytoecdysteroids significantly affected their toxicity toward P. interpunctella. Makisterone A was the most toxic of the four compounds towards P. interpunctella larvae.
    CONCLUSIONS:
    In conclusion, phytoecdysteroids ingestion evokes disruptive growth effects on P. interpunctella. This work supports a role for phytoecdysteroids in plant defence against phytophagous insects.
    Glucoliquiritin

    Catalog No: CFN95011
    CAS No: 93446-18-5
    Price: $318/10mg
    Alloisoimperatorin

    Catalog No: CFN95012
    CAS No: 35214-83-6
    Price: $338/5mg
    Oleuroside

    Catalog No: CFN95099
    CAS No: 116383-31-4
    Price: $288/20mg
    7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB)

    Catalog No: CFN95139
    CAS No: 79559-60-7
    Price: $268/20mg
    Rhamnocitrin 3-apiosyl-(1->2)-glucoside

    Catalog No: CFN95145
    CAS No: 148031-68-9
    Price: $318/10mg
    3,7,25-Trihydroxycucurbita-5,23-dien-19-al

    Catalog No: CFN95150
    CAS No: 85372-65-2
    Price: $318/5mg
    Apigenin 7-O-(6''-O-malonylglucoside)

    Catalog No: CFN95163
    CAS No: 86546-87-4
    Price: $318/5mg
    Andrographidine A

    Catalog No: CFN95210
    CAS No: 113963-37-4
    Price: $318/10mg
    (3beta,22alpha)-26-(beta-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl 2-O-(6-deoxy-alpha-mannopyranosyl)-beta-glucopyranosiduronic acid

    Catalog No: CFN95321
    CAS No: 107783-53-9
    Price: $318/20mg
    Pinocembroside

    Catalog No: CFN95444
    CAS No: 75829-43-5
    Price: $118/20mg