Platycoside E

Platycoside E
Product Name Platycoside E
CAS No.: N/A
Catalog No.: CFN90786
Molecular Formula: C69H112O38
Molecular Weight: 1549.6 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Targets: IFN-γ | IL Receptor
Source: The roots of Platycodon grandiflorum.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Platycoside E can significantly promote the production of the sera ovalbumin (OVA)-specific IgG2a and IgG2b antibody in the OVA-immunized mice.
Inquire / Order:
Technical Inquiries:
Tel: +86-27-84237783
Fax: +86-27-84254680

1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to:

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Enzyme Inhib Med Chem.2019, 34(1):134-143
  • Korean J of Pharmacognosy2020, 51,49-54.
  • Environ Toxicol.2022, 37(3):514-526.
  • Toxicol In Vitro.2022, 81:105346.
  • Int J Mol Sci.2020, 21(24):9369.
  • Bioorg Med Chem.2018, 26(14):4201-4208
  • J Nat Med.2020, 74(1):65-75
  • Pharmaceuticals (Basel).2021, 14(7):633.
  • Horticulturae2021, 7(1),5.
  • Plos One.2020, 10.1371
  • Polygalasaponin XLIX

    Catalog No: CFN95117
    CAS No: 1033593-12-2
    Price: $318/10mg
    Ilexoside XLVIII

    Catalog No: CFN91698
    CAS No: 129095-76-7
    Price: $318/5mg
    Asperosaponin VI

    Catalog No: CFN99766
    CAS No: 39524-08-8
    Price: $88/20mg
    Araloside VII

    Catalog No: CFN80402
    CAS No: 340982-22-1
    Price: Inquiry(
    Hederacoside D

    Catalog No: CFN90184
    CAS No: 760961-03-3
    Price: $218/20mg
    Polygalasaponin E

    Catalog No: CFN95138
    CAS No: 882664-72-4
    Price: $368/5mg
    Polygalasaponin II

    Catalog No: CFN91789
    CAS No: 162857-62-7
    Price: $318/5mg
    Polygalasaponin F

    Catalog No: CFN90171
    CAS No: 882664-74-6
    Price: $158/20mg
    Polygalasaponin V

    Catalog No: CFN90650
    CAS No: 162857-65-0
    Price: $188/20mg
    Polygalacin D

    Catalog No: CFN93351
    CAS No: 66663-91-0
    Price: Inquiry(
    Vaccine, 2008, 26(27-28):3452-60.
    Contribution of the glycidic moieties to the haemolytic and adjuvant activity of platycodigenin-type saponins from the root of Platycodon grandiflorum.[Pubmed: 18501482 ]
    Platycodin D (PD), platycodin D3 (PD3), and Platycoside E (PE) were the platycodigenin-type saponins isolated from the root of Platycodon grandiflorum.
    To assess the potential contribution of the glycidic chains to the biological activities and elucidate the structure-activity relationships of the platycodigenin-type saponins, these three saponins were evaluated for their haemolytic activities and adjuvant potentials on the cellular and humoral immune responses of mice against ovalbumin (OVA). Among three saponins, the ranking of the haemolytic activity was PD>PD3>PE (P<0.001). PD and PD3 could significantly enhance mitogen- and OVA-induced splenocyte proliferation in the OVA-immunized mice (P<0.001). The order of increasing OVA-stimulated splenocyte proliferation was PD>PD3>PE (P<0.05, P<0.01, or P<0.001). The sera OVA-specific IgG, IgG1, IgG2a and IgG2b antibody levels in the OVA-immunized mice were significantly enhanced by PD and PD3. However, PE only significantly promoted the production of the sera OVA-specific IgG2a and IgG2b antibody in the OVA-immunized mice. Adjuvant potentials of PD on antibody responses were higher than those of PD3 and PE (P<0.05, P<0.01, or P<0.001). Meanwhile, PD also significantly enhanced the mRNA expression of cytokines IL-2, IFN-gamma, IL-4, and IL-10 and transcription factors T-bet and GATA-3 in mice splenocyte induced by Con A (P<0.05, P<0.01, or P<0.001).
    These results suggested that the number of sugar residues in the glycidic chains attached to C-3 of aglycone could affect the haemolytic and adjuvant activities of platycodigenin-type saponins, and that PD had immunological adjuvant activity, and simultaneously elicited a Th1 and Th2 immune response by regulating gene expression of Th1/Th2 cytokines and transcription factors.
    Bruceoside A

    Catalog No: CFN95080
    CAS No: 63306-30-9
    Price: $318/10mg

    Catalog No: CFN95171
    CAS No: 87095-77-0
    Price: $318/10mg

    Catalog No: CFN95198
    CAS No: 75412-95-2
    Price: $318/10mg
    Nardoaristolone B

    Catalog No: CFN95203
    CAS No: 1422517-82-5
    Price: $398/5mg
    Isolappaol A

    Catalog No: CFN95224
    CAS No: 131400-96-9
    Price: $333/10mg
    Rosmarinyl glucoside

    Catalog No: CFN95297
    CAS No: 910028-78-3
    Price: $413/5mg
    Glaucoside C

    Catalog No: CFN95300
    CAS No: 81474-89-7
    Price: $318/5mg
    Deoxy euphorbia factor L1

    Catalog No: CFN95340
    CAS No: 247099-01-0
    Price: $318/10mg
    New compound 10

    Catalog No: CFN95343
    CAS No: N/A
    Price: $318/5mg
    Cannabisin M

    Catalog No: CFN95436
    CAS No: 1831134-13-4
    Price: $318/5mg