Momordin II

Momordin II
Product Name Momordin II
CAS No.: 95851-41-5
Catalog No.: CFN92562
Molecular Formula: C47H74O18
Molecular Weight: 927.1 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Targets: DNA/RNA Synthesis
Source: The fruits of Momordica cochinchinensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Price:
Highly purified Momordin II inhibits cell-free protein synthesis, releases adenine from rat liver ribosomes and from DNA, and has no RNase activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Kor.J.Herbol.2024, 39(3):23-35
  • Int J Vitam Nutr Res.2022, doi: 10.1024.
  • J Appl Biol Chem2021, 64(3):245-251.
  • Food Chem.2016, 191:81-90
  • BMC Complement Altern Med.2014, 14:352
  • Antioxidants (Basel).2021, 10(11): 1802.
  • J.Korean Society of Grassland&Forage Science2023, 43(3):138-147.
  • Chinese Journal of Tissue Engineering Research2024, 28(8):1149-1154.
  • Biotechnol Bioeng.2020, 117(7):2198-2208.
  • National Academy Science Letters2023, s40009.
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    Life Sci. 1999;65(14):1485-91.
    Preparation of highly purified momordin II without ribonuclease activity.[Pubmed: 10530800]

    METHODS AND RESULTS:
    Momordin II, a ribosome-inactivating protein from Momordica charantia seeds, was purified by a procedure involving a series of chromatographies on S-Sepharose, Sephadex G-50, CM-Sepharose, and Red Sepharose columns.
    CONCLUSIONS:
    Highly purified Momordin II inhibited cell-free protein synthesis, released adenine from rat liver ribosomes and from DNA, and had no RNase activity.
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