Pseudoginsenoside RT1
Pseudoginsenoside RT1 can cause a decrease in blood pressure, an increase in heart rate and an increase in spontaneous contractility of the uterus.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Pharmaceutical Biology, 2008 ,37 (1) :42-45.
Biological Activity of Crude Extract and Saponin Pseudoginsenoside-RT1 Derived from the Fruit of Randia siamensis[Reference:
WebLink]
METHODS AND RESULTS:
Ursolic acid (1), pseudoginsenoside-RP 1 (2), and Pseudoginsenoside RT1 (3) were isolated from the fruit of Randia siamensis. 13 C NMR spectroscopy was particularly useful in confirming the structures of these components. Studies with rats showed that saponin 3 caused a decrease in blood pressure, an increase in heart rate and an increase in spontaneous contractility of the uterus.
CONCLUSIONS:
Also, a crude ethanol extract of the fruit of R. siamensis exhibited acute ichthyotoxic activity.
Phytochemistry. 1994 Mar 30;35(5):1319-24.
Oleanolic acid saponins from root bark of Aralia elata.[Pubmed:
7764823]
Three new oleanolic acid glycosides, tarasaponins I-III, were isolated as their methyl esters from the root bark of Aralia elata together with four known glycosides, the methyl esters of chikusetsusaponins IVa, IV, 28-desglucosyl-chikusetsusaponin IV and Pseudoginsenoside RT1.
METHODS AND RESULTS:
Tarasaponins I-III were characterized as oleanolic acid 3-O-[beta-D-glucopyranosyl(1-->3)][alpha-L-arabinofuranosyl(1-->4)[- beta-D-glucuronopyranoside, oleanolic acid 3-O-[beta-D-xylopyranosyl(1-->2)][beta-D-galactopyranosyl(1-->3)]-beta- D-glucuronopyranoside and beta-D-glucopyranosyl oleanolate 3-O-beta-D-galactopyranosyl(1-->3)-beta-D-glucuronopyranoside, respectively.
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