Methylophiopogonone A
Methylophiopogonone A is a natural product from Ophiopogon japonicus.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Korean Journal of Pharmacognosy2018, 49(1):76-83
J Ethnopharmacol.2024, 333:118415.
J. Pharm. Res. Int.2022, 34(58): pp.1-14.
Advances in Traditional Medicine 2021, 21:779-789.
J Appl Toxicol.2024, jat.4615.
Front Immunol.2017, 8:1542
Appl. Sci. 2021, 11(22), 10552
Natural Product Res.&Deve.2022, 1001-6880.
Int J Mol Sci.2022, 23(20):12516.
Int J Mol Sci.2023, 24(5):4505.
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Chemical & pharmaceutical bulletin,1993, 41(2), 391-393.
Comparative Studies on the Constituents of Ophiopogonis Tuber and Its Congeners. VII. Studies on the Homoisoflavonoids of the Subterranean Part of Ophiopogon japonicus KER-GAWLER cv. Nanus. [Reference:
WebLink]
METHODS AND RESULTS:
Six known homoisoflavonoidal compounds (1-6) and three new homoisoflavonoidal compounds (7-9) were isolated from the ether-soluble fraction of the subterranean part of Ophiopogon japonicus KER-GAWLER cv. Nanus. Among them, 1,2,3,4,5 and 6 were identified as Methylophiopogonone A (1), ophiopogonone A (2), methylophiopogonanone A (3), ophiopogonanone A (4), JE-III (5) and desmethylisoophiopogonone B (6), respectively.
CONCLUSIONS:
The structures of compounds 7-9 were elucidated as 5,7,2'-trihydroxy-6-methyl-3-(3', 4'-methylenedioxybenzyl)chromone (7), 5,7,2'-trihydroxy-8-methyl-3-(3', 4'-methylenedioxybenzyl)chromone (8), and a racemate of 5-hydroxy-7,8-dimethoxy-6-methyl-3-(3', 4'-dihydroxybenzyl)chroman-4-one (9), respectively.
