Luteosporin

Luteosporin
Product Name Luteosporin
CAS No.: 2530-39-4
Catalog No.: CFN98567
Molecular Formula: C28H18O12
Molecular Weight: 546.44 g/mol
Purity: >=98%
Type of Compound: Quinones
Physical Desc.: Powder
Targets: PLA2
Source: The body of Cordyceps sienesis (Berkeley) Saccardo
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Luteosporin and xanthomegnin are pigments, they are suspected to be genotoxic carcinogens. Luteosporin inhibits porcine pancreatic phospholipase A2 (PLA2) with Ki values of 12.8 microM.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Int J Mol Sci.2022, 23(13):7115.
  • Plant Cell.2024, 158: 62.
  • Molecules.2019, 24(17):E3127
  • Life (Basel).2022, 12(10):1630.
  • Histol Histopathol.2022, 18518.
  • Nat Prod Sci.2016, 22(2)
  • BMC Plant Biol.2018, 18(1):122
  • Int J Mol Sci.2022, 23(21):13406.
  • J of the Korean Society of Cosmetics and Cosmetology2019, 225-231
  • Vet World.2023, 16(3):618-630.
  • 2-Hydroxy-1,4-naphoquinone

    Catalog No: CFN91715
    CAS No: 83-72-7
    Price: $30/20mg
    Juglone

    Catalog No: CFN90497
    CAS No: 481-39-0
    Price: $40/20mg
    2-Methoxy-1,4-naphthoquinone

    Catalog No: CFN95269
    CAS No: 2348-82-5
    Price: $70/20mg
    Plumbagin

    Catalog No: CFN90444
    CAS No: 481-42-5
    Price: $30/20mg
    Chimaphilin

    Catalog No: CFN95676
    CAS No: 482-70-2
    Price: $318/20mg
    7-(Hydroxymethyl)-2-methyl-1,4-naphthalenedione

    Catalog No: CFN95672
    CAS No: 145626-36-4
    Price: $318/10mg
    New compound 33

    Catalog No: CFN95706
    CAS No: N/A
    Price: $413/5mg
    Droserone

    Catalog No: CFN91989
    CAS No: 478-40-0
    Price: Inquiry(manager@chemfaces.com)
    Aristolindiquinone

    Catalog No: CFN93018
    CAS No: 86533-36-0
    Price: Inquiry(manager@chemfaces.com)
    2-Methoxystypandrone

    Catalog No: CFN97412
    CAS No: 85122-21-0
    Price: $318/5mg
    Cancer Res. 1984 Jul;44(7):2918-23.
    Genotoxicity of a variety of mycotoxins in the hepatocyte primary culture/DNA repair test using rat and mouse hepatocytes.[Pubmed: 6722817]

    METHODS AND RESULTS:
    Twenty-eight mycotoxins were studied in the hepatocyte primary culture/DNA repair test using rat and mouse hepatocytes. DNA repair synthesis was elicited by several compounds of unknown carcinogenicity, 5,6- dimethoxysterigmatocystin , versicolorins A and B, averufin , xanthomegnin , Luteosporin , and chrysazin , as well as by the carcinogenic myocotoxins , aflatoxin B1, sterigmatocystin, luteoskyrin , ochratoxin A, azaserine, mitomycin C, and actinomycin D.
    CONCLUSIONS:
    The positive results with compounds of unknown carcinogenicity suggest that they are possibly genotoxic carcinogens. The carcinogenic mycotoxins, penicillic acid, patulin, griseofulvin, and rugulosin , which did not elicit repair synthesis may be nongenotoxic carcinogens.
    J Antibiot (Tokyo). 1985 Jun;38(6):706-12.
    Two new inhibitors of phospholipase A2 produced by Penicillium chermesinum. Taxonomy, fermentation, isolation, structure determination and biological properties.[Pubmed: 3839502]

    METHODS AND RESULTS:
    Plastatin and the known fungal metabolite, Luteosporin, have been isolated from fermentations of Penicillium chermesinum as inhibitors of porcine pancreatic phospholipase A2 (PLA2). Structure 1 for plastatin was deduced from its spectroscopic properties. Plastatin and Luteosporin inhibited pancreatic PLA2 competitively with Ki values of 0.89 microM and 12.8 microM, respectively.
    CONCLUSIONS:
    PLA2 preparations from Naja naja and Crotalus adamanteus were not significantly inhibited by plastatin and Luteosporin.
    Naringin 4'-glucoside

    Catalog No: CFN95014
    CAS No: 17257-21-5
    Price: $338/5mg
    Selaginellin

    Catalog No: CFN95030
    CAS No: 941269-84-7
    Price: $338/5mg
    Bruceoside A

    Catalog No: CFN95080
    CAS No: 63306-30-9
    Price: $368/20mg
    Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside

    Catalog No: CFN95109
    CAS No: 868557-54-4
    Price: $338/5mg
    7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB)

    Catalog No: CFN95139
    CAS No: 79559-60-7
    Price: $268/20mg
    Bergaptol-beta-glucopyranoside

    Catalog No: CFN95186
    CAS No: 131623-13-7
    Price: $318/10mg
    Phyllanthusiin C

    Catalog No: CFN95260
    CAS No: 142674-52-0
    Price: $318/5mg
    (+)-Lariciresinol 4'-O-beta-D-Glucopyranosyl-(1->3)-beta-D-glucopyranoside

    Catalog No: CFN95283
    CAS No: 639857-95-7
    Price: $463/5mg
    Deoxy euphorbia factor L1

    Catalog No: CFN95340
    CAS No: 247099-01-0
    Price: $318/10mg
    Isochlorogenic acid C 4'-O-glucoside

    Catalog No: CFN95405
    CAS No: N/A
    Price: $413/5mg