Rubioncolin C

Rubioncolin C
Product Name Rubioncolin C
CAS No.: 132242-52-5
Catalog No.: CFN89245
Molecular Formula: C27H22O6
Molecular Weight: 442.46 g/mol
Purity: >=98%
Type of Compound: Quinones
Physical Desc.: Powder
Targets: NF-kB
Source: The roots and rhizomes of Rubia podantha.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $368/5mg
Rubioncolin C shows good cytotoxicity with IC50 value of 1.53 uM and NF-κB inhibitory activity with IC50 value of 2.97 uM.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • J Ginseng Res.2020, 44(4):611-618.
  • Journal of Food Composition and Analysis2021, 100:103905.
  • Nat Prod Sci.2018, 24(3):206
  • Nat Prod Sci.2018, 24(2):109-114
  • Molecules.2021, 26(13):4081.
  • Molecules.2023, 28(10):4121.
  • Molecules.2021, 26(18):5665.
  • Biomimetics (Basel).2022, 7(4):154.
  • Food Chem.2022, 373(Pt B):131364.
  • J Sep Sci.2020, 201901140
  • Juglone

    Catalog No: CFN90497
    CAS No: 481-39-0
    Price: $40/20mg
    2-Methoxy-1,4-naphthoquinone

    Catalog No: CFN95269
    CAS No: 2348-82-5
    Price: $70/20mg
    Plumbagin

    Catalog No: CFN90444
    CAS No: 481-42-5
    Price: $30/20mg
    Chimaphilin

    Catalog No: CFN95676
    CAS No: 482-70-2
    Price: $318/20mg
    7-(Hydroxymethyl)-2-methyl-1,4-naphthalenedione

    Catalog No: CFN95672
    CAS No: 145626-36-4
    Price: $318/10mg
    New compound 33

    Catalog No: CFN95706
    CAS No: N/A
    Price: $413/5mg
    Droserone

    Catalog No: CFN91989
    CAS No: 478-40-0
    Price: Inquiry(manager@chemfaces.com)
    Aristolindiquinone

    Catalog No: CFN93018
    CAS No: 86533-36-0
    Price: Inquiry(manager@chemfaces.com)
    2-Methoxystypandrone

    Catalog No: CFN97412
    CAS No: 85122-21-0
    Price: $318/5mg
    Rubioncolin C

    Catalog No: CFN89245
    CAS No: 132242-52-5
    Price: $368/5mg
    Phytochemistry. 2017 Nov 10;145:153-160.
    Rubipodanones A-D, naphthohydroquinone dimers from the roots and rhizomes of Rubia podantha.[Pubmed: 29132078 ]
    Four previously undescribed naphthohydroquinone dimers named rubipodanones A-D, together with 19 known quinones containing three known napthohydroquinone dimers named Rubioncolin C, methyl 5-hydroxy-dinaphtho[1,2-2',3']furan-7,12-dione-6-carboxylate and rubialatin B, were isolated from the roots and rhizomes of Rubia podantha.
    METHODS AND RESULTS:
    Their structures and absolute configurations were determined mainly by NMR, X-ray diffraction, and computational methods. Rubipodanones C and D, the glycosides of rubipodanone A and a pair of C-3 epimer, are the first identified dimeric napthohydroquinone glycosides from the Rubia plants. All naphthohydroquinone dimers were evaluated for their cytotoxicities against ten tumor cell lines and effects on the tumor-associated NF-κB signaling pathway, and Rubioncolin C showed the best cytotoxicity with IC50 value of 1.53 μM and NF-κB inhibitory activity with IC50 value of 2.97 μM.
    CONCLUSIONS:
    These results also demonstrated that the key roles of C-3 configuration and sugar group for biological activities of rubipodanone C.
    Arjungenin

    Catalog No: CFN95039
    CAS No: 58880-25-4
    Price: $318/20mg
    Dihydrolicoisoflavone

    Catalog No: CFN95073
    CAS No: 164163-92-2
    Price: $333/5mg
    5-Hydroxy-1-(4-hydroxyphenyl)-7-phenyl-3-heptanone (AO 2210)

    Catalog No: CFN95137
    CAS No: 105955-04-2
    Price: $318/10mg
    3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside

    Catalog No: CFN95228
    CAS No: 51768-39-9
    Price: $413/5mg
    Sphenanlignan

    Catalog No: CFN95245
    CAS No: 866347-36-6
    Price: $318/5mg
    Menisperine

    Catalog No: CFN95318
    CAS No: 25342-82-9
    Price: $318/10mg
    Oxytroflavoside A

    Catalog No: CFN95463
    CAS No: 1391144-80-1
    Price: $318/5mg
    Isorhamnetin-3-O-rutinoside-7-O-glucoside

    Catalog No: CFN95494
    CAS No: 55481-91-9
    Price: $318/5mg
    Mahuannin B

    Catalog No: CFN95554
    CAS No: 82796-37-0
    Price: $318/5mg
    11-Keto-ganoderic acid DM

    Catalog No: CFN95593
    CAS No: N/A
    Price: $413/5mg