Longiferone B

Longiferone B
Product Name Longiferone B
CAS No.: 1639810-67-5
Catalog No.: CFN89084
Molecular Formula: C15H22O
Molecular Weight: 218.34 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Oil
Targets: NO | NOS | COX
Source: The rhizomes of Boesenbergia longiflora (Wall.) Kuntze.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price:
Longiferone B shows anti-inflammatory activity against NO release with IC50 values of 21.0 uM, it also suppresses the iNOS and COX-2 mRNA expression.
Inquire / Order: manager@chemfaces.com
Technical Inquiries: service@chemfaces.com
Tel: +86-27-84237783
Fax: +86-27-84254680

Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
  • Korean J. Medicinal Crop Sci.2023, 31(6):388-395.
  • Heliyon.2023, 9:e21652.
  • Arch Biochem Biophys.2020, 687:108384.
  • Microchemical Journal2024, 200:110475
  • Int J Mol Sci.2023, 24(5):4505.
  • US20170000760 A12016, 42740
  • Appl. Sci.2020, 10(20),7374.
  • Antioxidants2022, 11(2),234.
  • J Nat Med.2018, 72(3):734-744
  • J of App. Res. on Med&Aromatic Plants2020, 100291.
  • Isocalamendiol

    Catalog No: CFN98278
    CAS No: 25330-21-6
    Price: Inquiry(manager@chemfaces.com)
    10-O-Acetylisocalamendiol

    Catalog No: CFN96767
    CAS No: 1432064-69-1
    Price: Inquiry(manager@chemfaces.com)
    4-Cadinen-7-ol

    Catalog No: CFN98081
    CAS No: 217650-27-6
    Price: Inquiry(manager@chemfaces.com)
    (-)-Cadin-4,10(15)-dien-11-oic acid

    Catalog No: CFN95246
    CAS No: 1124353-23-6
    Price: $318/5mg
    3-Acetoxy-4-cadinen-8-one

    Catalog No: CFN97485
    CAS No: 923950-05-4
    Price: Inquiry(manager@chemfaces.com)
    9-Oxoageraphorone

    Catalog No: CFN99071
    CAS No: 105181-06-4
    Price: Inquiry(manager@chemfaces.com)
    1,3,5-Cadinatriene-3,8-diol

    Catalog No: CFN97514
    CAS No: 941227-27-6
    Price: Inquiry(manager@chemfaces.com)
    8-Hydroxy-4-cadinen-3-one

    Catalog No: CFN97550
    CAS No: 97372-53-7
    Price: Inquiry(manager@chemfaces.com)
    Lacinilene C

    Catalog No: CFN98653
    CAS No: 41653-72-9
    Price: Inquiry(manager@chemfaces.com)
    7-Hydroxycadalene

    Catalog No: CFN89214
    CAS No: 2102-75-2
    Price: Inquiry(manager@chemfaces.com)
    J Ethnopharmacol. 2014 Jun 11;154(2):453-61
    Anti-inflammatory activity of compounds from Boesenbergia longiflora rhizomes.[Pubmed: 24786574 ]

    METHODS AND RESULTS:
    The isolation of the CHCl3 fraction from Boesenbergia longiflora rhizomes led to the isolation of three new daucane sesquiterpenes, which were identified as 8-hydroxy-dauca-9, 11-diene-7-one (longiferone A; 1), dauca-8, 11-diene-7-one (Longiferone B; 2) and dauca-8, 11-diene-7, 10-dione (longiferone C; 3); together with four known flavonoids, six known diarylheptanoids as well as one sterol. The Longiferone B (2) and longiferone C (3) showed anti-inflammatory activity against NO release with IC50 values of 21.0 and 31.3μM, respectively. Longiferone B (2) also suppressed the iNOS and COX-2 mRNA expression. Moreover, the flavonoids and diarylheptanoids inhibited NO and TNF-α production in a dose dependent manner.
    CONCLUSIONS:
    This study demonstrated that sesquiterpenes, diarylheptanoids and some methoxyflavonoids found in Boesenbergia longiflora are responsible for anti-inflammatory activity.
    Isorubrofusarin 10-gentiobioside

    Catalog No: CFN95119
    CAS No: 200127-93-1
    Price: $338/10mg
    Cassiaglycoside II

    Catalog No: CFN95130
    CAS No: 2241081-56-9
    Price: $368/5mg
    Isovalerylshikonin

    Catalog No: CFN95222
    CAS No: 52387-14-1
    Price: $318/10mg
    Quercetin-3'-glucoside

    Catalog No: CFN95271
    CAS No: 19254-30-9
    Price: $318/10mg
    4'-O-Methyllucenin II (Diosmetin 6,8-di-C-glucoside)

    Catalog No: CFN95344
    CAS No: 98813-28-6
    Price: $318/10mg
    12beta-Acetoxy-3beta-hydroxy-7,11,15,23-tetraoxo-lanost-8,20-diene-26-oic acid

    Catalog No: CFN95468
    CAS No: 1085338-75-5
    Price: $318/5mg
    3-Oxo-alpha-ilexanolic acid

    Catalog No: CFN95496
    CAS No: N/A
    Price: $413/5mg
    beta-Hydroxyacteoside

    Catalog No: CFN95499
    CAS No: 109279-13-2
    Price: $318/10mg
    8-epi-Confertin

    Catalog No: CFN95509
    CAS No: 110115-60-1
    Price: $318/5mg
    Methyl ganoderate F

    Catalog No: CFN95584
    CAS No: 98665-08-8
    Price: $368/5mg