Leptomerine
Leptomerine (IC₅₀ = 2.5 mM) shows potent anticholinesterasic activity.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Plant Cell Physiol.2018, 59(1):128-141
Applied Biological Chemistry2024, 67:66.
Univerzita Karlova2021, 20.500.11956.
BMB Rep.2018, 51(5):249-254
Mol Med Rep.2015, 12(5):7789-95
Int J Mol Sci.2024, 25(17):9673.
Industrial Crops and Products2019, 140:111612
Appl. Sci.2021, 11(19),9343.
Oncotarget.2017, 8(64):108006-108019
Foods.2020, 9(10):1348.
Related and Featured Products
Molecules. 2010 Dec 13;15(12):9205-13.
Alkaloids from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer disease.[Pubmed:
21160449]
Esenbeckia leiocarpa Engl. (Rutaceae), popularly known as guarantã, goiabeira, is a native tree from Brazil.
METHODS AND RESULTS:
Bioactivity-guided fractionation of the ethanol stems extract afforded the isolation of six alkaloids: leiokinine A, Leptomerine, kokusaginine, skimmianine, maculine and flindersiamine. All isolated compounds were tested for acetyl cholinesterase inhibition, in vitro and displayed anticholinesterasic activity. The alkaloid Leptomerine showed the highest activity (IC₅₀ = 2.5 mM), similar to that of the reference compound galanthamine (IC₅₀ = 1.7 mM).
CONCLUSIONS:
The results showed for the first time the presence of alkaloids Leptomerine and skimmianine in E. leiocarpa (Engl.) with potent anticholinesterasic activity.
3,7,25-Trihydroxycucurbita-5,23-dien-19-al
Catalog No: CFN95150
CAS No: 85372-65-2
Price: $318/5mg
Vanillic acid glucoside
Catalog No: CFN95257
CAS No: 32142-31-7
Price: $368/10mg
Bidenoside C
Catalog No: CFN95266
CAS No: 700877-55-0
Price: $318/5mg
Lyciumamide B
Catalog No: CFN95286
CAS No: 1647111-41-8
Price: $318/5mg
Corymboside
Catalog No: CFN95292
CAS No: 73543-87-0
Price: $318/10mg
Glaucoside C
Catalog No: CFN95300
CAS No: 81474-89-7
Price: $318/5mg
2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene
Catalog No: CFN95428
CAS No: 1608462-12-9
Price: $318/10mg
New compound 17
Catalog No: CFN95466
CAS No: N/A
Price: $318/5mg
2,6-Dihydroxyacetophenone-4-O-[4',6'-(S)-hexahydroxydiphenoyl]-beta-D-glucose
Catalog No: CFN95470
CAS No: 1781226-44-5
Price: $318/5mg
Hosenkoside D
Catalog No: CFN95521
CAS No: 156823-94-8
Price: $318/5mg
