Ilicol
Pinocembrin and Ilicol inhibit root growth and show IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. They reduce Allium cepa cell division without chromosome aberrations.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Natural Product Sciences2024, 30(1):8-13.
Preprints2022, 202211.0388.v1.
Arch Toxicol.2017, 91(10):3225-3245
Food Chem.2024, 452:139555.
Pharmaceuticals (Basel).2024, 17(1):108.
Journal of Mushroom2023, 21(4):215-221.
RSC Advances2017, 86
Cancers (Basel).2023, 15(1):293.
Toxins (Basel).2022, 14(12):824.
Mol Neurobiol.2023, 60(12):7196-7207.
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Chem Biodivers. 2013 Jul;10(7):1295-304.
Phytotoxicity of secondary metabolites isolated from Flourensia oolepis S.F.Blake.[Pubmed:
23847074]
The aim of this study was to isolate the active principles of Flourensia oolepis S.F.Blake (Asteraceae), which completely inhibited the germination of Raphanus sativus seeds at 10 mg/ml.
METHODS AND RESULTS:
Flavanone pinocembrin and sesquiterpene Ilicol, were isolated by bioassay-guided fractionation. They were active both against monocot and dicot seeds. Pinocembrin was the most active compound, with an IC50 (germination) value of 0.24, 3.40, 3.28, and 3.55 mM against Panicum miliaceum, Avena sativa, Lactuca sativa, and R. sativus, respectively; Ilicol, however, exhibited IC50 (germination) values of 0.67, 2.73, 5.25, and 9.66 mM for the same species, respectively. Pinocembrin and Ilicol inhibited root growth and showed IC50 (root growth) values of 0.199, 14.68, 8.05, 7.69 mM, and 1.22, 2.90, 7.35, 8.07 mM, against P. miliaceum, A. sativa, L. sativa, and R. sativus, respectively. Pinocembrin and Ilicol reduced Allium cepa cell division without chromosome aberrations.
