Hesperetin 5-O-glucoside
Hesperetin 5-O-glucoside has hypocholesterolemic effect.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Eur J Pharmacol.2021, 906:174220.
Foods.2022, 11(12):1708.
Molecules.2023, 28(10):4062.
Nutr Cancer.2022, 1-13.
Industrial Crops and Products2022, 188:115596.
Arch Biochem Biophys.2020, 687:108363.
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J Nat Prod. 1991 Jan-Feb;54(1):218-24.
Antihyperlipidemic effect of flavonoids from Prunus davidiana.[Pubmed:
2045817]
METHODS AND RESULTS:
Blood lipid levels in rats with hyperlipidemia resulting from high-fat feeding were determined after ip administration of an MeOH extract of Prunus davidiana stems and its flavonoid components, (+)-catechin, prunin (= naringenin 7-O-glucoside), and Hesperetin 5-O-glucoside. Administration of the MeOH extract for 3 days produced a significant decrease of blood triglyceride and total cholesterol, and the atherogenic index was also improved.
CONCLUSIONS:
(+)-Catechin was shown to be effective in reducing the elevated level of triglyceride. Prunin and Hesperetin 5-O-glucoside did not show such an effect in high-fat-fed hypertriglyceridemic rats, but they did exhibit a significant hypocholesterolemic effect.
