Enhydrin chlorohydrin | CAS:38230-99-8

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Extraction of Yacon Leaves Enhances Enhydrin Degradation[Reference: WebLink]

Sesquiterpene lactones (SLs) with various activities, which are primarily composed of enhydrin, are the primary constituents in the leaves of the yacon, Smallanthus sonchifolius (Peoepp. & Endl.) H. Robinson. To study the effect of heat extract on the degradation of enhydrin, the hydrolyzed products were isolated and their anticancer activity was assayed.
METHODS AND RESULTS:
The decoction extraction of yacon leaves under heat could enhance enhydrin degradation. However, the degradation was not observed when the pure compound (i.e., enhydrin) was refluxed. The major degradation products of enhydrin were isolated and identified to be 6-deacetyldeepoxydihydroxyenhydrin (1), deepoxydihydroxyenhydrin (2) and Enhydrin chlorohydrin (3). In addition, the cytotoxic activity of the SLs obtained against human gastric cancer cells (MGC80-3) indicated that enhydrin is stronger than its degradation products.
CONCLUSIONS:
Our results further confirmed that the traditional tea using way of yacon leaves in the folks is reasonable.

Product Name	Enhydrin chlorohydrin
CAS No.:	38230-99-8
Catalog No.:	CFN97746
Molecular Formula:	C₂₃H₂₉ClO₁₀
Molecular Weight:	500.93 g/mol
Purity:	>=98%
Type of Compound:	Sesquiterpenoids
Physical Desc.:	Powder
Source:	The herbs of Smallanthus sonchifolius
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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