Dodoviscin J can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells.
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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J Nat Prod. 2012 Apr 27;75(4):699-706.
Isoprenylated flavonoid and adipogenesis-promoting constituents of Dodonaea viscosa.[Pubmed:
22512738]
METHODS AND RESULTS:
Ten new isoprenylated flavonol derivatives, dodoviscin A(1), dodoviscin B(2), dodoviscin C(3),dodoviscin D(4), dodoviscin E(5), dodoviscin F(6), dodoviscin G(7), Dodoviscin H(8), Dodoviscin I (9) , Dodoviscin J (10), and seven known compounds (11-17) were isolated from the aerial parts of Dodonaea viscosa.
CONCLUSIONS:
Compounds 1, 2, 4, 5, 7-9, 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3-methoxyflavone (11), 5,7,4'-trihydroxy-3',5'-bis(3-methyl-2-buten-1-yl)-3,6-dimethoxyflavone (12), 5,7,4'-trihydroxy-3'-(4-hydroxy-3-methylbutyl)-5'-(3-methyl-2-buten-1-yl)-3,6-dimethyoxyflavone (13), sakuranetin (14), and blumeatin (15) promoted adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. Compounds 1, 13, and 15 also enhanced the accumulation of lipid droplets and induced upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4.
