Desoxygambogenin

Desoxygambogenin
Product Name Desoxygambogenin
CAS No.: 173614-93-2
Catalog No.: CFN92088
Molecular Formula: C38H48O6
Molecular Weight: 600.8 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Oil
Targets: HIV
Source: The herbs of Garcinia hanburyi Hook. f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $318/10mg
Desoxygambogenin is a cytotoxic xanthone, it has anti-HIV-1 activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Planta Med. 2007 Jan;73(1):33-40. Epub 2006 Nov 21.
    Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi.[Pubmed: 17117343]
    Three new caged xanthones, 7-methoxydesoxymorellin (1), 2-isoprenylforbesione (2) and 8,8a-epoxymorellic acid (3), together with nine known caged xanthones were isolated from the EtOAc extracts of resin and fruits of Garcinia hanburyi.
    METHODS AND RESULTS:
    The structures were determined by spectroscopic methods. Most of the isolated compounds showed significant cytotoxicities against a panel of mammalian cancer cell lines. Compound 3, together with the known compounds desoxymorellin, morellic acid, gambogic acid, hanburin, forbesione and dihydroisomorellin, exhibited anti-HIV-1 activity in the reverse transcriptase (RT) assay while the known compounds Desoxygambogenin and dihydroisomorellin were found moderately active in the syncytium assay.
    CONCLUSIONS:
    This work represents the first report on the anti-HIV-1 activities of caged xanthones.
    Phytochemistry. 1996 Feb;41(3):815-20.
    Cytotoxic xanthones from Garcinia hanburyi.[Pubmed: 8835458]

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