Demethylcephalotaxinone
Demethylcephalotaxinone is a natural product from Cephalotaxus fortunei.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Acta Botanica Sinica,1980,22(2):56-60.
Studies on Alkaloids of Cephalotaxus sinensis (Rehd et Will.)Li[Reference:
WebLink]
METHODS AND RESULTS:
Seven alkaloids were isolated from Cephalotaxus sinensis(Rehd.et Wils.)Li and were identified by elements analysis,melting point and spectral data.Six of them are known alkaloids:cephalotaxine(Ⅰ),Ⅱ-hydroxycephalotaxine(Ⅱ),drupacine(Ⅲ), Demethylcephalotaxinone(Ⅳ),c-3epi-wilsonine(Ⅴ)and wilsonine(Ⅵ).
CONCLUSIONS:
Cephalo- taxine is the major alkaloid of this plant.(Ⅰ-Ⅳ)are alkaloid of Cephalotaxus type and another two(Ⅴ-Ⅵ)are alkaloid of homoerythrina type.(Ⅶ)seems to be a new alkaloid.Its structure wiltbe studied further.
J Am Chem Soc. 1975 Apr 30;97(9):2507-16.
Total synthesis of the Cephalotaxus alkaloids. Cephalotaxine, cephalotaxinone, and demethylcephalotaxinone[Reference:
WebLink]
METHODS AND RESULTS:
Cephalotaxine (1), the major alkaloid produced by several species of Cephalotaxus (plum-yews), has been synthesized as its racemate in eight steps from 1-prolinol (4) and 3,4-methylenedioxyphenylacetyl chloride (3).
CONCLUSIONS:
Cephalotaxinone (22) and Demethylcephalotaxinone (19), minor alkaloids which normally occur with cephalotaxine, have been prepared as intermediates in this synthesis.
