4-Hydroxycephalotaxine
4-Hydroxycephalotaxine is a natural product from Cephalotaxus fortunei.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Research Square2024, rs-4398438
Iranian Journal of Pharmaceutical Sciences2021, 17(2):25-36
Food Hydrocolloids2024, 152:109898
Food Chem.2024, 436:137768.
LWT2020, 130:109535
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Pharm Biol.2021, 59(1):134-145.
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Antiphytoviral activity of alkaloids from Cephalotaxus sinensis[Reference:
WebLink]
The evaluation of pesticidal activity and the isolation of plant allelochemicals can lead to the discovery of new pesticides.
METHODS AND RESULTS:
This study confirmed that Cephalotaxus sinensis, an important Chinese medicinal species, has excellent activities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) both indoors and outdoors; its control of the TMV is comparable to that of a commercialized antiviral agent (VA; active ingredient = a mixture of moroxydine hydrochloride and copper acetate). Using bioassay-guided fractionation, we isolated eight active alkaloids, which were identified as drupacine, 11-hydroxycephalotaxine, cephalancetine A, isocephalotaxine, cephalotaxine β-N-oxide, 4-Hydroxycephalotaxine, wilsonine and cephalotaxine.
CONCLUSIONS:
At the same dosage, the inactivation activities against TMV were not significantly different among drupacine, 11-hydroxycephalotaxine, cephalotaxine and VA (inhibition ratio = 50.76% to 53.41%).
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