Convolamine
Convolamine may have antihypoxic, immunomodulating, and anti-inflammatory activity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Chemistry of Natural Compounds, 2014 , 50 (3) :576-577.
Acylation of Convolvine by Anhydrides of Mono- and Dicarboxylic Acids[Reference:
WebLink]
METHODS AND RESULTS:
The alkaloid contents of Convolvulus subhirsutus and C. pseudocanthabrica growing in various regions of Uzbekistan, Kazakhstan, and Tadzhikistan were previously investigated and were found to include ~10 tropane alkaloids [ 1 , 2 ]. The alkaloid composition and content depended on the habitat. Thus, total alkaloids in C. subhirsutus growing in Uzbekistan was 0.6–0.75% (aerial part) and 0.6–1.6% (roots) [ 2 , 3 ]; in Tadzhikistan, 0.12%(aerial part) [ 4 ]. The main alkaloids in all plants were nortropine derivatives convolvine ( 1 , 3,4-dimethoxybenzoyloxynortropane) and Convolamine (3,4-dimethoxybenzoyloxytropane), which amounted to 40–50% of the total. The alkylation and acylation of the NH group in 1 were studied [ 3 ].
CONCLUSIONS:
Preliminary tests showed that the synthesized compounds included some with pronounced antihypoxic, immunomodulating, and anti-inflammatory activity.
Chemistry of Natural Compounds,1986,22(1): 74-78.
The NMR investigation of alkaloids. IX.13 C NMR spectra and stereochemistry of convolvine, convolamine, convoline, convolidine, subhirsine, and 6-hydroxyhyoscyamine[Reference:
WebLink]
METHODS AND RESULTS:
On the basis of the results of a study of the13C NMR spectra, a correlation has been made of the CSs of the13C carbon nuclei with the structure and stereochemistry of the tropane alkaloids convolvine, Convolamine, convoline, convolidine, subhirsine, and 6-hydroxyhyoscyamine. It has been established that the N-CH3 group in Convolamine and the N-OH group in convoline are oriented equatorially, and the N-CH3 in hydroxyhyoscyamine axially.
