Cochinchinenin C
There is a synergistic interaction between loureirin A and Cochinchinenin C, and the fluorescence quenching of HSA by loureirin A (or Cochinchinenin C) is a combined quenching procedure (dynamic and static quenching).
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
The Catharanthus Genome2022,35-83.
In Vitro Cellular & Developmental Biology - Plant2022, 58:972-988.
Natural Product Res.&Deve.2022, 1001-6880.
Molecules.2021, 26(4):817.
Food Engineering Progress2019, 23(3)209-216
J Ethnopharmacol.2020, 260:112988.
Journal of Ginseng Research2022, j.jgr.2022.09.005.
Front Aging Neurosci.2019, 11:230
Viruses2023, 15(6), 1377
Environ Toxicol.2020, doi: 10.1002
Related and Featured Products
Eur J Med Chem. 2015 Mar 26;93:492-500.
Comparison between loureirin A and cochinchinenin C on the interaction with human serum albumin.[Pubmed:
25734332]
METHODS AND RESULTS:
The interactions of loureirin A (LA) and Cochinchinenin C (CC) with human serum albumin (HSA) under simulated physiological conditions (pH = 7.4) have been studied with fluorescence, UV-vis absorption spectroscopic method and molecular docking technique. The results indicated that there was a synergistic interaction between LA and Cochinchinenin C, and the fluorescence quenching of HSA by LA (or Cochinchinenin C) was a combined quenching procedure (dynamic and static quenching). At low compound concentrations, the quenching constants KSV of Cochinchinenin C was larger than that of LA, which meant the Cochinchinenin C efficacy may be better than that of LA. The negative △H and △S values suggested hydrogen bonds and van der Waals forces played the major role in the binding of LA (or Cochinchinenin C) to HSA.
CONCLUSIONS:
The efficiency of energy transfer and distance between the compounds and HSA was calculated. Moreover, the results of synchronous and three-dimensional fluorescence demonstrated that the HSA microenvironment was changed in the presence of LA (or Cochinchinenin C). Finally, the binding of LA (or Cochinchinenin C) to HSA was modeled by molecular docking, which is in good accordance with the experimental studies.
Obovatol
Catalog No: CFN95054
CAS No: 83864-78-2
Price: $318/5mg
1,3,6-Trihydroxy-2-methylanthraquinone 3-O-(6'-O-acetyl)-alpha-L-rhamnosyl-(1->2)-Beta-D-glucoside
Catalog No: CFN95095
CAS No: 87686-87-1
Price: $218/10mg
(1E)-3-methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one
Catalog No: CFN95219
CAS No: 1393342-06-7
Price: $413/5mg
Nortrachelogenin-8'-O-beta-glucoside
Catalog No: CFN95234
CAS No: 858127-38-5
Price: $368/10mg
Diosmin Impurity 5
Catalog No: CFN95311
CAS No: 122087-66-5
Price: $318/10mg
3',5-Dihydroxy-4',6,7-trimethoxyflavanone
Catalog No: CFN95316
CAS No: 90850-99-0
Price: $318/5mg
New compound 14
Catalog No: CFN95381
CAS No: N/A
Price: $413/5mg
Malabaricone A
Catalog No: CFN95477
CAS No: 63335-23-9
Price: $318/10mg
(3,4-Dihydroxyphenyl)methyl 3-(beta-D-glucopyranosyloxy)-4-hydroxybenzoate
Catalog No: CFN95531
CAS No: 877461-90-0
Price: $318/10mg
1-Phenylethyl beta-D-glucoside
Catalog No: CFN95574
CAS No: 93199-03-2
Price: $318/5mg