(-)-Cinchonidine

(-)-Cinchonidine
Product Name (-)-Cinchonidine
CAS No.: 485-71-2
Catalog No.: CFN70118
Molecular Formula: C19H22N2O
Molecular Weight: 294.3 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Price: $30/20mg
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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  • J Ethnopharmacol.2022, 282:114574.
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  • ACS Pharmacol. Transl. Sci.2022, 5,7,479-490
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    Analytica Chimica Acta, 2009, 639(1-2):67-72.
    Resolution of (+)-cinchonine and (-)-cinchonidine by phase-modulation fluorescence spectroscopy.[Pubmed: 19345760 ]
    The different fluorescence lifetime profiles of the optical isomers (+)-cinchonine (CN) and (-)-Cinchonidine (CD) have been used to resolve their mixtures, on the basis of phase and modulation fluorescence lifetime measurements.
    METHODS AND RESULTS:
    To resolve mixtures of these compounds two distinct approaches have been used: simultaneous equations from phase-resolved and modulation-based fluorescence lifetime measurements.
    CONCLUSIONS:
    Results indicate that frequency domain fluorimetry is useful to resolve stereomeric compounds for determination without physical separation. The precision of the measurements gives RSD values of 5.2% and 4.0% for CD and CN, respectively. Detection limits with the modulation fluorescence lifetime method were 11.3 and 17.2 microM for CD and CN, respectively.
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