Cinalbicol

Phytochemistry. 2017 Jan;133:59-68.

Bioactive constituents from transformed root cultures of Nepeta teydea.[Pubmed: 28340896 ]

METHODS AND RESULTS:
A phytochemical study of an extract from transformed root cultures of Nepeta teydea, induced by Agrobacterium rhizogenes, led to the isolation of the following new compounds: the sesquiterpene (-)-Cinalbicol, the diterpene teydeadione (6,11,14-trihydroxy-12-methoxy-abieta-5,8,11,13,15-penten-7-one), a degraded C23-triterpene (teydealdehyde) and three fatty acid esters of lanosta-7,24-dien-3β-ol.
CONCLUSIONS:
The propyl ester of rosmarinic acid was also isolated for the first time from a natural source. In addition, two dehydroabietane diterpenes, eight triterpenes and eighteen known phenolic compounds were obtained. The antifeedant, cytotoxic and phytotoxic activities of the isolated compounds have also been investigated.

J Asian Nat Prod Res. 2009 Nov;11(11):958-61.

The sesquiterpenes from the roots of Cacalia roborowskii.[Pubmed: 20183260 ]

METHODS AND RESULTS:
A new sesquiterpene cacaroborin (1) was isolated from the roots of Cacalia roborowskii, together with three known ones, Cinalbicol (2), isopetasin (3), and 3alpha-angeloyloxylactone (4).
CONCLUSIONS:
The structure of compound 1 was elucidated as 1beta,10alpha-dihydroxy-8alpha-methoxyeremophil-7(11)-en-8beta,12-olide on the basis of spectral evidence (1D, 2D NMR, IR, EI-MS, and HR-ESI-MS) and X-ray diffraction analysis.