Carmine
Carmine is used in the manufacture of artificial flowers, paints, crimson ink, rouge, and other cosmetics, and is routinely added to food products such as yogurt, candy and certain brands of juice, the most notable ones being those of the ruby-red variety.There are many reported cases of immediate allergy after ingestion of foods containing cochineal and have a few reports of allergic contact dermatitis from carmine, suggests that carmine is an allergen.
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Int Immunopharmacol.2023, 123:110572.
Nutraceutical Research . 2021, 19(1),p90-105.
Plant Pathology2022, 13527
Oncol Rep.2021, 46(1):143.
Molecules.2022, 27(7):2360.
Sci Rep.2023, 13(1):13610.
Drug Des Devel Ther.2020, 14:969-976.
Hindawi J of Food Biochemistry2023, P17:8883860
Foods.2022, 11(6):882.
Biomed Pharmacother.2023, 163:114785.
Related and Featured Products
Dermatitis. 2011 Nov-Dec;22(6):348-9.
Allergic contact dermatitis from carmine in cosmetic blush.[Pubmed:
22653009]
Although there are many reported cases of immediate allergy after ingestion of foods containing cochineal, there are few reports of allergic contact dermatitis from Carmine.
METHODS AND RESULTS:
We present a rare case of allergic contact dermatitis due to Carmine. A 52-year-old female presented with an itchy erythema on her cheeks at the site where blush had been applied. Patch-tested with her cosmetics, she showed a positive reaction to the blush (30% in petrolatum) and to 0.2% (but not 0.1%) Carmine in petrolatum. In this case, the optimum patch-test concentration of Carmine was 0.2% in petrolatum.
J Clin Monit Comput. 2015 Jun 17.
Effects of indigo carmine intravenous injection on noninvasive and continuous total hemoglobin measurement.[Pubmed:
26076807]
The effects of an intravenous injection of indigo Carmine on noninvasive and continuous total hemoglobin (SpHb) measurement were retrospectively evaluated.
METHODS AND RESULTS:
The subjects were 21 patients who underwent elective gynecologic surgery under general anesthesia. During surgery, 5 mL of 0.4 % indigo Carmine was intravenously injected, and subsequent changes in SpHb concentrations were evaluated. The results demonstrate that the pre-injection SpHb level was 10 g/dL, and the minimum post-injection SpHb level was 8.3 g/dL. The amount of decrease was 1.8 g/dL. The time to reach the minimum value was 4 min, and the time to return to the pre-injection value was 15 min. The decrease in SpHb was greater in the group with a perfusion index (PI) < 1.4 than in the group with a PI > 1.4.
CONCLUSIONS:
The assessment of SpHb after an intravenous injection of indigo Carmine necessitates caution.
Open Orthop J. 2013;7:8-11.
Effects of indigo carmine on human chondrocytes in vitro.[Pubmed:
23341851]
Joint infections following or accompanying superficious soft tissue infections are severe complication in orthopedic surgery. The use of intra-articular blue staining is a helpful method to visualize a fistula and to differentiate between superficial and intra-articular infections. Regarding this clinical implication data about the effects of indigo Carmine, a frequently used blue staining substance, on cartilage is missing.
METHODS AND RESULTS:
The hypothesis of this study was that indigo Carmine damages human chondrocytes in a time and concentration dependent manner. Human chondrocytes were isolated from donors with osteoarthritis who were treated with TKA. Cells were cultivated and treated with different concentrations of indigo Carmine for 5 and 10 minutes. Morphologic damage was examined by light microscopy. Toxicity was quantified by counting vital cell number and lactate dehydrogenase (LDH) expression. Analysis by light microscopy showed defected cell structure and loss of cell number after treatment with 100% indigo Carmine for 10 minutes. Treatment with 10% and 1% indigo Carmine showed no significant cell defects and loss of cells. Counting vital cell number showed loss of vital cells after treatment with 100% and 10% indigo Carmine for 10 minutes. LDH expression was significantly increased after treatment with 100% indigo Carmine.Toxic effects were shown after treatment with indigo Carmine.
CONCLUSIONS:
Therefore, it should be used in 1:100 dilution. This is both, sufficient for visualizing a fistula in a possible clinical application and could be protective for chondrocytes.
