Calystegine C2
Calystegine C2, the 2-epimer of calystegine C1, exhibits an inhibitory activity against beta-glucosidase and beta-galactosidase.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Phytochemistry,1997,45( 2): 425-9.
Calystegine alkaloides from Duboisia leichhardtii.[Reference:
WebLink]
METHODS AND RESULTS:
Pentahydroxy-nor-tropane alkaloids, calystegines C1 and C2, were isolated from the leaves of greenhouse-cultivated Duboisia leichhardtii, together with calystegines B1, B2 and B4. Calystegine C1 is a potent inhibitor of beta-glucosidase and beta-galactosidase, whereas Calystegine C2 exhibited no significant inhibitory activity against these enzymes.
CONCLUSIONS:
Only Calystegine C2, the 2-epimer of calystegine C1, among calystegines isolated to date exhibited an inhibitory activity against all alpha-mannosidases tested.
