Aricine
Aricine has cytotoxicity.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Biochem Biophys Res Commun.2017, 494(3-4):587-593
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Phytotherapy Research,1988,2(1):25-29.
In vitro cytotoxicity testing of natural products using guinea‐pig ear keratinocytes[Reference:
WebLink]
METHODS AND RESULTS:
A simple test is described in which the inhibition of uptake of [G-3H]thymidine into guinea-pig ear keratinocytes in vitro, has been used as an assessment for cytotoxicity of a series of alkaloids. The alkaloids tested include emetine, colchicine, coronaridine, ajmaline, Aricine, vincristine, leurosine, quinamine, 3-epiquinamine, quinine, quinidinone, cichonidine, berberine and atropine.
Natural Product Communications, 2012, 7(11):1441-1444.
A new monoterpenoid oxindole alkaloid from Hamelia patens micropropagated plantlets.[Reference:
WebLink]
METHODS AND RESULTS:
Chemical studies on Hamelia patens (Rubiaceae) micropropagated plantlets allowed production of a new monoterpenoid oxindole alkaloid, named (-)-hameline (7), together with eight known alkaloids, tetrahydroalstonine (1), Aricine (2), pteropodine (3), isopteropodine (4), uncarine F (5), speciophylline (6), palmirine (8), and rumberine (9). The structure of the new alkaloid was assigned on the basis of 1D and 2D NMR spectroscopy, mass spectrometry, and molecular modeling.
