Antibiotic PF 1018
Antibiotic PF 1018 is an insecticidal agent.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Turkish Journal of Pharmaceutical Sciences2022, DOI: 10.4274
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Phytomedicine.2015, 22(14):1262-8
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Industrial Crops and Products2019, 140:111612
Mol Med Rep.2014, 9(5):1653-9
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The Journal of Antibiotics, 1994, 47(5):571-80.
PF1018, a novel insecticidal compound produced by Humicola sp.[Pubmed:
8040055]
METHODS AND RESULTS:
A new insecticidal compound PF1018(Antibiotic PF 1018) was isolated from the culture broth of Humicola sp. It exhibited insecticidal activity against a wide range of critical pest species.
CONCLUSIONS:
The structure of PF1018 was determined to be (7aS)-2-((2E)-1-hydroxy-3-((1S,3aR,4R,5R,7aR)-3a,4,5,7 a-tetrahydro-1,3,5,7- tetramethyl-5,1-((3S)-(Z)-2,3-dimethylpropeno)-1H-inden-4-yl )-2- propenylidene)pyrrolizidine-1,3-dione, by NMR spectral analyses coupled with X-ray crystallographic analysis and chemical degradation study.
