Ajugatakasin A
Ajugatakasin A is a natural product from Ajuga ciliata Bunge.
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Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to
24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Bioscience Biotechnology & Biochemistry , 1997 , 61 (9) :1518-1522.
Ajugatakasins A and B, New Diterpenoids from Ajuga decumbens, and Feeding Stimulative Activity of Related Neoclerodane Analogs toward the Turnip Sawfly[Reference:
WebLink]
Adults of the turnip sawfly, Athalia rosae ruficornis, are strongly attracted to the leaves of Ajuga decumhens (Labiatae).
METHODS AND RESULTS:
Specific feeding stimulants of the sawfly were examined in the leaf surface extracts of A. decumbens. Among seven neoclerodane diterpenoids isolated from the extracts, two new analogs, Ajugatakasin A and ajugatakasin B, were characterized as 6α,18-diacetoxy-1β,12-ditigloyloxy-4α,17-epoxyneoclerod-13-en-15,16-olide and its 1β,12-di-(2-methylbutanoyl)-oxy analog, respectively.
CONCLUSIONS:
Among these analogs, clerodendrin D, a very minor constituent which possesses a tetrahydrofurofuran moiety, was identified as the feeding stimulant for A. rosae ruficornis, while the other analogs with an α,β-unsaturated γ-lactone moiety were found to be completely inactive in the sawfly feeding test.
Natural Product Communications , 2006 , 1 (3) :183-189.
Isolation and identification of neo-clerodane diterpenes from Ajuga nipponensis Makino[Reference:
WebLink]
An extract of the aerial parts of Ajuga nipponensis Makino was examined by HPLC for neo-clerodane diterpenes.
METHODS AND RESULTS:
The suitability of reversed-phase HPLC for the semi-preparative fractionation of this extract was explored, resulting in the isolation of two new neo-clerodane diterpenes, which we have named ajuganipponin A, (12S)-1β,6α,19-triacetoxy-4α,18-epoxy-12- tigloyl-neo-clerod-13-en-15,16-olide (AJNP A, 1), and ajuganipponin B, (12S)-6α,19-diacetoxy-4α,18-epoxy-12-tigloyl-neoclerod-13-en-15, 16-olide (AJNP B, 6). In addition, ajugamarins A2 and F4, ajugamacrin B, ajugacumbin A and Ajugatakasin A, were newly isolated compounds from A. nipponensis, along with the previously reported ajugamarins A1, B2 and L2 (ajugacumbin B).
CONCLUSIONS:
The structures of all the isolated compounds were unambiguously elucidated based on extensive NMR spectral studies (one and two-dimensional experiments) and their reversed-phase chromatographic behavior was established. The antifeedant activity of the isolated diterpenes against Spodoptera littoralis is also reported here.
